Document and Entity Information - USD ($)	12 Months Ended
Document and Entity Information - USD ($)	Dec. 31, 2018	Mar. 07, 2019	Jun. 30, 2018
Document And Entity Information [Abstract]
Document Type	10-K
Amendment Flag	false
Document Period End Date	Dec. 31, 2018
Document Fiscal Year Focus	2018
Document Fiscal Period Focus	FY
Trading Symbol	RKDA
Entity Registrant Name	ARCADIA BIOSCIENCES, INC.
Entity Central Index Key	0001469443
Current Fiscal Year End Date	--12-31
Entity Well-known Seasoned Issuer	No
Entity Voluntary Filers	No
Entity Current Reporting Status	Yes
Entity Emerging Growth Company	true
Entity Small Business	true
Extended Transition Period	true
Entity Shell Company	false
Entity Filer Category	Non-accelerated Filer
Entity Common Stock, Shares Outstanding		4,777,419
Entity Public Float			$ 39,400,000

Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 11,998	$ 9,125
Short-term investments	9,825	3,898
Accounts receivable	165	1,231
Unbilled revenue	3	4
Inventories — current	181	229
Prepaid expenses and other current assets	704	560
Total current assets	22,876	15,047
Property and equipment, net	395	299
Inventories — noncurrent	746	1,168
Other noncurrent assets	7	56
Total assets	24,024	16,570
Current liabilities:
Accounts payable and accrued expenses	2,645	2,496
Amounts due to related parties	29	29
Unearned revenue — current	96	1,000
Other current liabilities	284
Total current liabilities	3,054	3,525
Unearned revenue — noncurrent		2,038
Common stock warrant liabilities	5,083
Other noncurrent liabilities	3,072	3,000
Total liabilities	11,209	8,563
Stockholders’ equity:
Common stock, $0.001 par value—150,000,000 shares authorized as of December 31, 2018 and December 31, 2017; 4,774,919 and 2,134,154 shares issued and outstanding as of December 31, 2018 and December 31, 2017, respectively.	45	42
Additional paid-in capital	191,136	175,223
Accumulated deficit	(178,366)	(167,257)
Accumulated other comprehensive loss		(1)
Total stockholders’ equity	12,815	8,007
Total liabilities and stockholders’ equity	$ 24,024	$ 16,570

Consolidated Balance Sheets (Parenthetical) - $ / shares	Dec. 31, 2018	Dec. 31, 2017
Statement Of Financial Position [Abstract]
Common stock, par value	$ 0.001	$ 0.001
Common stock, authorized	150,000,000	150,000,000
Common stock, issued	4,774,919	2,134,154
Common stock, outstanding	4,774,919	2,134,154

Consolidated Statements of Operations and Comprehensive Loss - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Revenues:
Total revenues	$ 1,464,000	$ 4,026,000
Operating expenses:
Research and development	6,069,000	7,407,000
Selling, general and administrative	11,604,000	10,651,000
Total operating expenses	18,334,000	18,341,000
Loss from operations	(16,870,000)	(14,315,000)
Interest expense		(747,000)
Other income, net	394,000	281,000
Initial loss on common stock warrant and common stock adjustment feature liabilities	(4,000,000)
Change in fair value of common stock warrant and common stock adjustment feature liabilities	9,561,000
Offering costs	(2,555,000)
Loss on extinguishment of debt		(900,000)
Net loss before income taxes	(13,470,000)	(15,681,000)
Income tax provision	(10,000)	(26,000)
Net loss attributable to common stockholders	$ (13,480,000)	$ (15,707,000)
Net loss per share attributable to common stockholders:
Basic and diluted	$ (3.58)	$ (7.28)
Weighted-average number of shares used in per share calculations:
Basic and diluted	3,766,419	2,156,201
Other comprehensive income, net of tax
Unrealized gains on available-for-sale securities		$ 18,000
Other comprehensive income		18,000
Comprehensive loss attributable to common stockholders	$ (13,480,000)	(15,689,000)
Product
Revenues:
Total revenues	657,000	514,000
Operating expenses:
Cost of product revenues	661,000	283,000
License
Revenues:
Total revenues	150,000	1,470,000
Contract Research And Government Grants
Revenues:
Total revenues	$ 657,000	$ 2,042,000

Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	June Offering [Member]	June Purchase Agreement [Member]	Common Stock [Member]	Common Stock [Member] Securities Purchase Agreement [Member]	Common Stock [Member] June Purchase Agreement [Member]	Additional Paid-In Capital [Member]	Additional Paid-In Capital [Member] June Offering [Member]	Additional Paid-In Capital [Member] Securities Purchase Agreement [Member]	Additional Paid-In Capital [Member] June Purchase Agreement [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]
Stockholders Equity, Beginning Balance at Dec. 31, 2016	$ 22,198			$ 44			$ 173,723				$ (151,550)	$ (19)
Stockholders Equity, Beginning Balance, Shares at Dec. 31, 2016				2,224,384
Issuance of shares related to employee stock purchase plan	24						24
Issuance of shares related to employee stock purchase plan, Shares				1,964
Stock-based compensation	1,474						1,474
Other comprehensive income	18											18
Exchange of membership interest in unconsolidated entity for common stock				$ (2)			2
Exchange of membership interest in unconsolidated entity for common stock, Shares				(92,194)
Net loss	(15,707)										(15,707)
Stockholders Equity, Ending Balance at Dec. 31, 2017	8,007			$ 42			175,223				(167,257)	(1)
Stockholders Equity, Ending Balance, Shares at Dec. 31, 2017				2,134,153
Impact of adoption of Topic 606 (Note 5) \| Topic 606 [Member]	2,371										2,371
Issuance of shares related to employee stock option exercises	$ 963						963
Issuance of shares related to employee stock option exercises, Shares	44,354			44,354
Issuance of shares related to employee stock purchase plan	$ 6						6
Issuance of shares related to employee stock purchase plan, Shares				1,122
Issuance of shares			$ 4,978		$ 1	$ 2			$ (1)	$ 4,976
Issuance of shares, Shares					1,201,634	1,392,345
Issuance of placement agent warrants	526	$ 427					526	$ 427
Common stock adjustment feature	8,378						8,378
Offering costs related to June Offering			$ (912)							$ (912)
Stock-based compensation	1,550						1,550
Issuance of shares related to reverse stock split, Shares				1,311
Other comprehensive income	1											1
Net loss	(13,480)										(13,480)
Stockholders Equity, Ending Balance at Dec. 31, 2018	$ 12,815			$ 45			$ 191,136				$ (178,366)	$ 0
Stockholders Equity, Ending Balance, Shares at Dec. 31, 2018				4,774,919

Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
Consolidated Statements of Cash Flows - USD ($)	Dec. 31, 2018	Dec. 31, 2017
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (13,480,000)	$ (15,707,000)
Adjustments to reconcile net loss to cash used in operating activities:
Initial loss on common stock warrant and common stock adjustment feature liabilities	4,000,000
Change in fair value of common stock warrant and common stock adjustment feature liabilities	(9,561,000)
Offering costs	2,555,000
Depreciation	154,000	279,000
Gain on disposal of equipment	(3,000)	(1,000)
Net amortization of investment premium and discount	(193,000)	(89,000)
Stock-based compensation	1,550,000	1,474,000
Loss on sale of investments		2,000
Accretion of debt discount		98,000
Loss on extinguishment of debt		900,000
Write down of inventory	310,000	0
Changes in operating assets and liabilities:
Accounts receivable	1,066,000	(882,000)
Unbilled revenue	2,000	179,000
Inventories	160,000	183,000
Prepaid expenses and other current assets	(151,000)	324,000
Other noncurrent assets		11,000
Accounts payable and accrued expenses	176,000	87,000
Amounts due to related parties	(1,000)	(1,000)
Unearned revenue	(312,000)	(822,000)
Other current liabilities	25,000
Other noncurrent liabilities	72,000
Net cash used in operating activities	(13,631,000)	(13,965,000)
CASH FLOWS FROM INVESTING ACTIVITIES:
Proceeds from sale of property and equipment	10,000	4,000
Purchases of property and equipment	(250,000)	(79,000)
Purchases of investments	(29,885,000)	(19,405,000)
Proceeds from sales and maturities of investments	24,150,000	66,658,000
Net cash (used in) provided by investing activities	(5,975,000)	47,178,000
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from issuance of common stock and warrants under Purchase Agreement	10,000,000
Payments of offering costs relating to Purchase Agreement	(1,308,000)
Proceeds from issuance of common stock and warrants from June Offering	14,000,000
Payments of offering costs relating to June Offering	(1,182,000)
Payments of debt extinguishment costs		(1,125,000)
Proceeds from exercise of stock options and purchases through ESPP	969,000	24,000
Payments on notes payable		(25,000,000)
Net cash provided by (used in) financing activities	22,479,000	(26,101,000)
Net increase in cash and cash equivalents	2,873,000	7,112,000
Cash and cash equivalents — beginning of period	9,125,000	2,013,000
Cash and cash equivalents — end of period	11,998,000	9,125,000
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
Cash paid for interest		746,000
Cash paid for income taxes	34,000	2,000
NONCASH TRANSACTIONS:
Offering costs in accounts payable and accrued expenses at end of period	23,000	50,000
Common stock warrants issued to placement agent and included in offering costs related to Purchase Agreement	526,000
Common stock warrants issued to placement agent and included in offering costs related to June Offering	239,000
Proceeds from sale of fixed assets included in prepaid expenses and other current assets		7,000
Reclassification of unearned revenue to other short term liabilities	259,000
Reclassification of common stock adjustment feature liability balance to equity	$ 8,378,000
Exchange of membership interest in unconsolidated entity for common stock		$ 2,000

Description of Business

12 Months Ended

Dec. 31, 2018

Accounting Policies [Abstract]

Description of Business

Note 1. Description of Business

Organization

Arcadia Biosciences, Inc. (the "Company"), was incorporated in the state of Arizona in 2002 and maintains its headquarters in Davis, California, with additional facilities in Phoenix, Arizona, and American Falls, Idaho. The Company was reincorporated in Delaware in March 2015.

We are a consumer-driven, agricultural food ingredient company. We aim to create value across the agricultural production and supply chain beginning with enhanced crop productivity for farmers and ultimately delivering accelerated innovation in nutritional quality consumer foods. We use state of the art gene-editing technology and advanced breeding techniques to naturally enhance the nutritional quality of grains and oilseeds to address the rapidly evolving trends in consumer health and nutrition. In addition, we have developed high value crop productivity traits designed to enhance farm economics.

In February 2012, the Company formed Verdeca LLC (“Verdeca,” see Note 7), which is jointly owned by us with Bioceres, Inc. (“Bioceres”), a U.S. wholly owned subsidiary of Bioceres, S.A., an Argentine corporation. Bioceres, S.A. is an agricultural investment and development cooperative. Verdeca, which is consolidated by the Company, was formed to develop and deregulate soybean varieties using both partners’ agricultural technologies.

Reverse Stock Split

In January 2018, the Company’s board of directors approved a reverse split of 1:20 on the Company’s issued and outstanding common stock which became effective on January 23, 2018. All issued and outstanding common stock, options to purchase common stock and per share amounts contained in the consolidated financial statement have been retroactively adjusted to reflect the reverse stock split for all periods presented. The reverse stock split did not change the total number of authorized shares of common stock which remained at one hundred and fifty million shares.

Liquidity, Capital Resources, and Going Concern

The accompanying consolidated financial statements have been prepared on a going concern basis, which contemplates the realization of assets and the satisfaction of liabilities during the normal course of business. Since inception, the Company has financed its operations primarily through equity and debt financings. As of December 31, 2018, the Company had an accumulated deficit of $178.4 million, cash and cash equivalents of $12.0 million, and short-term investments of $9.8 million. For the years ended December 31, 2018 and 2017, the Company had net losses of $13.5 million and $15.7 million, respectively, and net cash used in operations of $13.6 million and $14.0 million, respectively. The Company believes that its existing cash, cash equivalents and investments will be insufficient to meet its anticipated cash requirements for at least through March 2020, and thus raises substantial doubt about the Company’s ability to continue as a going concern. The financial statements do not include any adjustments that might result from the outcome of this uncertainty.

The Company may seek to raise additional funds through debt or equity financings. The Company may also consider entering into additional partner arrangements. The sale of additional equity would result in dilution to the Company’s stockholders. The incurrence of debt would result in debt service obligations, and the instruments governing such debt could provide for additional operating and financing covenants that would restrict operations. If the Company does require additional funds and is unable to secure adequate additional funding at terms agreeable to the Company, the Company may be forced to reduce spending, extend payment terms with suppliers, liquidate assets, or suspend or curtail planned development programs. Any of these actions could materially harm the business, results of operations and financial condition.

Summary of Significant Accounting Policies

12 Months Ended

Dec. 31, 2018

Accounting Policies [Abstract]

Summary of Significant Accounting Policies

Note 2. Summary of Significant Accounting Policies

Basis of Presentation and Principles of Consolidation

The consolidated financial statements include the accounts of the Company and Verdeca LLC. All intercompany balances and transactions have been eliminated in consolidation. The Company prepares its consolidated financial statements in conformity with accounting principles generally accepted in the United States of America, or U.S. GAAP (“GAAP”), and with the rules of the Securities and Exchange Commission. The Company uses a qualitative approach in assessing the consolidation requirement for variable interest entities ("VIEs"). This approach focuses on determining whether the Company has the power to direct the activities of the VIE that most significantly affect the VIE’s economic performance and whether the Company has the obligation to absorb losses, or the right to receive benefits, that could potentially be significant to the VIE. For all periods presented, the Company has determined that it is the primary beneficiary of Verdeca, which is a VIE. The Company evaluates its relationships with the VIEs upon the occurrence of certain significant events that affect the design, structure or other factors pertinent to the primary beneficiary determination. Verdeca LLC has no operations, assets or liabilities as of and for the years ended December 31, 2018 and 2017.

Use of Estimates

The preparation of consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions in the Company’s consolidated financial statements and notes thereto. Significant estimates and assumptions made by management included the determination of the provision for income taxes, stock-based compensation, fair value of certain equity instruments, costs to complete government grants and research contracts, and net realizable value of inventory. Management bases its estimates on historical experience and on various other market-specific and relevant assumptions that management believes to be reasonable under the circumstances. Actual results could differ from those estimates.

Cash and Cash Equivalents

The Company considers any liquid investments with a stated maturity of three months or less at the date of purchase to be cash equivalents. Cash and cash equivalents consist of cash on deposit with banks. The Company limits cash investments to financial institutions with high credit standings; therefore, management believes that there is no significant exposure to any credit risk in the Company’s cash and cash equivalents. However, as of December 31, 2018 and 2017, a substantial portion of the Company’s cash in depository accounts is in excess of the federal deposit insurance limits.

Investments in Equity and Debt Securities

The Company uses the equity method to account for investments in equity securities if the investment provides the Company the ability to exercise significant influence over operating and financial policies of the investee. The Company includes its proportionate share of earnings and/or losses of the equity method investee in its Consolidated Statements of Operations and Comprehensive Loss. The carrying value of the equity investments is reported using the equity method in the Consolidated Balance Sheets. On March 31, 2017, the Company and Vilmorin USA (“VUSA”) entered into a non-cash exchange agreement, which the Company transferred to VUSA the Company’s entire membership interest in Limagrain Cereal Seeds LLC and VUSA transferred to the Company 92,194 shares of the Company’s common stock held by Limagrain. The Company recorded the retirement of the shares using the cost method, resulting in an equity reclassification between common stock par value and additional paid-in capital

Investments in equity securities in which the Company holds less than 20% voting interest and on which the Company does not have the ability to exercise significant influence, and do not have readily determinable fair values are accounted for under the cost method. Cost method investments are originally recorded at cost and are reported on the Consolidated Balance Sheets.

Investments in debt securities are carried at fair value and classified as available-for-sale. Realized gains and losses on available-for-sale securities are included in other income — net in the Consolidated Statements of Operations and Comprehensive Loss. Unrealized gains and losses, net of deferred taxes, on available-for-sale securities are included in the Consolidated Balance Sheets as a component of accumulated other comprehensive income. Securities classified as available-for-sale are reported as cash and cash equivalent, short-term investments or long-term investments in the Consolidated Balance Sheets based on the nature of the investments and maturity period. Short-term investments have maturities of less than a year and long-term investments have maturities of a year and greater from the balance sheet date. The Company’s debt securities are primarily comprised of U.S. government securities, treasury bills, commercial paper, corporate securities, and money markets. These available-for-sale investments are held in the custody of a major financial institution.

Other-than-Temporary Impairments on Investment

The Company regularly reviews each of its investments for impairment by determining if the investment has sustained an other-than-temporary decline in its value, in which case the investment is written down to its fair value by a charge to earnings. Factors that are considered by the Company in determining whether an other-than-temporary decline in value has occurred include (i) the market value of the investment in relation to its cost basis, (ii) the financial condition of the investment, and (iii) the Company’s intent and ability to retain the investment for a sufficient period of time to allow for recovery of the market value of the investment. As of December 31, 2018, and 2017, there was no impairment of the Company’s investments.

Accounts Receivable

Accounts receivable represents amounts owed to the Company from product sales, licenses and contract research and government grants. The carrying value of the Company’s receivables represents estimated net realizable values. The Company generally does not require collateral and estimates any required allowance for doubtful accounts based on historical collection trends, the age of outstanding receivables, and existing economic conditions. If events or changes in circumstances indicate that specific receivable balances may be impaired, further consideration is given to the collectability of those balances and the allowance is recorded accordingly. Past-due receivable balances are written off when the Company’s internal collection efforts have been unsuccessful in collecting the amounts due. The Company had no amounts reserved for doubtful accounts at December 31, 2018 and 2017 as the Company expected full collections of all accounts receivable balances as of each of these dates.

SONOVA® Gamma Linolenic Acid (“GLA”) Safflower Oil Inventory

Proprietary safflower plants are grown, producing seed with a high-GLA content. This seed is used for subsequent plantings or processed, and sold as GLA oil, including SONOVA 400 GLA safflower oils and SONOVA Ultra GLA safflower oil, which we refer to as our SONOVA products. Amounts inventoried consist primarily of fees paid to contracted cooperators to grow the crops and costs to process and store harvested seed. Inventory costs are tracked on a lot-identified basis and are included as cost of product revenues when sold. Inventories are stated at the lower of cost or net realizable value. The Company makes adjustments to inventory when conditions indicate that the net realizable value may be less than cost due to physical deterioration, obsolescence, changes in price levels, or other factors. Additional adjustments to inventory are made for excess and slow-moving inventory on hand that is not expected to be sold within a reasonable timeframe to reduce the carrying amount to its estimated net realizable value. The write downs to inventory are based upon estimates about future demand from the Company’s customers and distributors and market conditions.

The inventories—current line item in the balance sheet consists of the cost of oil inventory forecasted to be sold in the next 12 months, as of the balance sheet date. The inventories—noncurrent line item consists of oil and seed inventory expected to be used in production or sold beyond the next 12 months, as of the balance sheet date.

Raw materials inventories consist primarily of seed production costs incurred by our contracted cooperators. Finished goods inventories consist of GLA oil that is available for sale. The Company recorded a $310,000 write-down of inventory for the year ended December 31, 2018. A write-down was not recorded for the year ended December 31, 2017. Inventories consist of the following (in thousands):

	As of December 31,
	2018		2017
Raw Materials	$	41	$	45
Finished Goods		886		1,352
Inventories	$	927	$	1,397

Property and Equipment

Property and equipment acquisitions are recorded at cost. Provisions for depreciation are calculated using the straight-line method over the following average estimated useful lives of the assets:

	Years
Laboratory equipment	5
Software and computer equipment	3
Furniture and fixtures	7
Vehicles	5
Leasehold improvements	2-10	*

*	Leasehold improvements are depreciated over the shorter of the estimated life of the asset or the remaining life of the lease.

Impairment of Long-Lived Assets

The Company evaluates if events and circumstances have occurred that indicate the remaining estimated useful life of long-lived assets and identifiable intangible assets may warrant revision or that the remaining balance of these assets may not be recoverable. In evaluating for recoverability, the Company estimates the future undiscounted cash flows expected to result from the use of the assets and their eventual disposition. In the event that the balance of any asset exceeds the future undiscounted cash flow estimate, impairment is recognized based on the excess of the carrying amounts of the asset above its estimated fair value. As of December 31, 2018, and 2017, there was no impairment of the Company’s long-lived assets.

Fair Value of Financial Instruments

Fair value accounting is applied for all financial assets and liabilities and non-financial assets and liabilities that are recognized or disclosed at fair value in the consolidated financial statements on a recurring basis. Assets and liabilities recorded at fair value in the consolidated financial statements are categorized based upon the level of judgment associated with the inputs used to measure their fair value. Hierarchical levels, which are directly related to the amount of subjectivity associated with the inputs to the valuation of these assets or liabilities, are as follows:

•

Level 1 inputs are quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company can access at the measurement date.

•

Level 2 inputs are observable inputs other than quoted prices in active markets for identical assets and liabilities, quoted prices for identical or similar assets or liabilities in inactive markets, or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.

•

Level 3 inputs are unobservable inputs for the asset or liability.

The carrying values of the Company’s financial instruments, including cash equivalents, accounts receivable, and accounts payable, approximated their fair values due to the short period of time to maturity or repayment.

Concentration of Risk

Cash and cash equivalents are maintained with several financial institutions. Deposits held with banks may exceed the amount of insurance provided on such deposits. Generally, these deposits may be redeemed upon demand and are maintained with financial institutions with reputable credit and therefore bear minimal credit risk. The Company seeks to mitigate its credit risks by spreading such risks across multiple counterparties and monitoring the risk profiles of these counterparties.

Customer Concentration

Significant customers are those that represent greater than 10% of the Company’s total revenues or gross accounts receivable balance at each respective balance sheet date.

Customers representing greater than 10% of accounts receivable were as follows (in percentages):

	As of December 31,
	2018		2017
Customer A		—		18
Customer D		—		53
Customer E		—		24
Customer I		44		—
Customer M		34		1

Customers representing greater than 10% of total revenues were as follows (in percentages):

	For Year Ended December 31,
	2018		2017
Customer A		—		26
Customer D		19		18
Customer L		16		9
Customer I		13		2
Customer M		11		2
Customer K		—		14

Stock-Based Compensation

The Company recognizes compensation expense related to employee stock purchase plan and the cost of stock-based compensation awards made to employees and directors on a straight-line basis over the requisite service period, net of estimated forfeitures. Judgment is required in estimating the amount of stock-based awards that will be forfeited prior to vesting. Compensation expense could be revised in subsequent periods if actual forfeitures differ from those estimates. The Company has selected the Black-Scholes option-pricing model and various inputs to estimate the fair value of its stock-based awards. See Note 12 for additional information.

The Company accounts for compensation expense related to stock options granted to non-employees based on the fair values estimated using the Black-Scholes model. Stock options granted to non-employees are re-measured at each reporting date until the award is vested.

Income Taxes

The Company uses the asset and liability method of accounting for income taxes. Under this method, deferred tax assets and liabilities are determined based on the differences between the financial reporting and the tax bases of assets and liabilities and are measured using the enacted tax rates and laws that will be in effect when the differences are expected to reverse. A valuation allowance is provided when it is more likely than not that some portion or all of a deferred tax asset will not be realized.

Net Loss per Share

Basic net loss per share, which excludes dilution, is computed by dividing the net loss attributable to common stockholders by the weighted-average number of shares of common stock outstanding during the period. Diluted net loss per share reflects the potential dilution that could occur if securities or other contracts to issue common stock, such as stock options, convertible promissory notes, convertible preferred stock, redeemable convertible preferred stock and warrants, result in the issuance of common stock which share in the losses of the Company. Certain potential shares of common stock have been excluded from the computation of diluted net loss per share as their effect would be anti-dilutive. Such potentially dilutive shares are excluded when the effect would be to reduce the loss per share. Due to net losses, there is no impact on earnings per share calculation in applying the two-class method since the participating securities have no legal requirement to share in any losses.

Revenue Recognition

We derive our revenues from product revenues, licensing agreements, contract research agreements, and government grants.

Product Revenues

Our product revenues to date have consisted solely of sales of our SONOVA products. We generally recognize revenue from product sales upon sale to our third-party distributors or customers.

License Revenues

Our license revenues to date consist of up-front, nonrefundable license fees, annual license fees, and subsequent milestone payments that we receive under our research and license agreements. We have historically recognized nonrefundable up-front license fees and guaranteed, time-based payments as revenue proportionally over the expected development period. With the implementation of ASC Topic 606, revenue generated from up-front license fees are recognized upon execution of the agreement. We recognize annual license fees when it is probable that a material reversal will not occur.

Milestone fees are a variable consideration that is initially constrained and recognized only when it is probable that such amounts would not be reversed. The Company assesses when achievement of milestones is probable to determine the timing of revenue recognition for milestone fees. Milestones typically consist of significant stages of development for our traits in a potential commercial product, such as achievement of specific technological targets, completion of field trials, filing with regulatory agencies, completion of the regulatory process, and commercial launch of a product containing our traits. Given the seasonality of agriculture and time required to progress from one milestone to the next, achievement of milestones is inherently uneven, and our license revenues are likely to fluctuate significantly from period to period.

Contract Research Revenues

Contract research and government grant revenues consist of amounts earned from performing contracted research primarily related to breeding programs or the genetic engineering of plants for third parties. Contract research revenue is accounted for as a single performance obligation for which revenues are recognized over time using the input method (e.g. costs incurred to date relative to the total estimated costs at completion). In addition, we are entitled to receive a portion of the revenues generated from sales of products that incorporate our seed traits. Products expected to result from such contract research are in various stages of the product development cycle and we expect to generate revenues from the sale of any such products in as soon as the next nine to 18 months.

Government Grant Revenues

The Company receives payments from government entities in the form of government grants. Government grant revenue is accounted for as a single performance obligation for which revenues are recognized over time using the input method (e.g. costs incurred to date relative to the total estimated costs at completion). The Company’s obligation with respect to these agreements is to perform the research on a best-efforts basis. Given the nature and uncertain timing of receipt of government grants and timing of eligible research and development expenses, such revenues are likely to fluctuate significantly from period to period.

Unearned Revenue

The Company defers revenue to the extent that cash received in conjunction with a license agreement, contract or grant exceeds the revenue recognized in accordance with Company policies.

Cost of Product Revenues

Cost of product revenues relates to the sale of our SONOVA products and consists of in-licensing and royalty fees, any adjustments or write-downs to inventory, as well as the cost of raw materials, including inventory and third-party services costs related to procuring, processing, formulating, packaging, and shipping our SONOVA products.

Research and Development Expenses

Research and development expenses consist of costs incurred in the discovery, development, and testing of our products and products in development incorporating our traits. These expenses consist primarily of employee salaries and benefits, fees paid to subcontracted research providers, fees associated with in-licensing technology, land leased for field trials, chemicals and supplies, and other external expenses. These costs are expensed as incurred. Additionally, as disclosed in Note 13, the Company is required from time to time to make certain milestone payments in connection with the development of technologies. These milestone payments are expensed at the time the milestone is achieved and deemed payable.

Change in the Estimated Fair Value of Common Stock Warrant Liabilities and Common Stock Adjustment Feature Liability

Change in the estimated fair value of common stock warrant liabilities and common stock adjustment feature liability is comprised of the fair value remeasurement of the liabilities associated with the Private Placement and June Private Placement. See Note 11.

Recent Accounting Pronouncements

12 Months Ended

Dec. 31, 2018

Accounting Changes And Error Corrections [Abstract]

Recent Accounting Pronouncements

Note 3. Recent Accounting Pronouncements

In May 2014, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2014-09, Revenue from Contracts with Customers, which requires an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. The ASU replaces most existing revenue recognition guidance in U.S. GAAP. In August 2015, the FASB issued ASU No. 2015-14, Revenue from Contracts with Customers (Topic 606): Deferral of Effective Date, which defers the effective date of ASU No. 2014-09 by one year allowing early adoption as of the original effective date January 1, 2017. The standard was adopted on January 1, 2018. See Note 6.

In January 2016, the FASB issued ASU No. 2016-01, Financial Instruments – Overall (Subtopic 825-10): Recognition and Measurement of Financial Assets and Financial Liabilities. The amendments in this update impacts classification, additional fair value measurement, impairment assessment of equity investments and current required disclosures. This standard is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years, with early adoption permitted if the entity meets certain early application guidance. The Company adopted ASU No. 2016-01 in the current year with no material impact to the consolidated financial statements.

In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842). Based on the new standard, lessees would recognize lease assets and lease liabilities for those leases classified as operating leases under previous GAAP and disclose qualitative and quantitative information about leasing arrangements with terms longer than 12 months. The new standard allows a modified-retrospective approach to adoption and is effective for interim and annual periods beginning on January 1, 2019. The adoption will require recording right-of-use assets and corresponding lease obligation liabilities for the current operating leases. Additionally, in July 2018, the FASB issued ASU No. 2018-10, Codification Improvements to Topic 842, Leases and ASU No. 2018-11, Leases (Topic 824) – Targeted Improvements, both of which are also being evaluated. The Company expects that the adoption of ASU No. 2016-02 will not have a material impact on our Consolidated Statements of Operations and Comprehensive Loss. See Note 14.

In June 2016, the FASB issued ASU No. 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments. The amendments affect loans, debt securities, trade receivables, net investments in leases, off-balance-sheet credit exposures, reinsurance receivables, and any other financial assets not excluded from the scope that have the contractual right to receive cash. The amendments in this update are effective for fiscal years beginning after December 15, 2019, including interim periods within those fiscal years. The Company is currently evaluating the impact of the adoption of ASU No. 2016-13 on its consolidated financial statements.

In August 2016, the FASB issued ASU No. 2016-15, Statement of Cash Flows (Topic 230): Classification of Certain Cash Receipts and Cash Payments. The amendments address cash flow issues such as debt prepayment or debt extinguishment costs and zero-coupon debt instruments. The amendments in this update are effective for fiscal years beginning after December 15, 2018, and interim periods within fiscal years beginning after December 15, 2019. Early adoption is permitted, including adoption in an interim period. The amendments are to be applied using a retrospective transition method to each period presented. If it is impractical to retrospectively apply, it can be applied prospectively as of the earliest date practicable. The Company adopted ASU No. 2016-15 in the current year with no material impact to the consolidated financial statements.

In May 2017, the FASB issued ASU No. 2017-09, Compensation – Stock Compensation (Topic 718): Scope of Modification Accounting. The amendments affect any entity that changes the terms or conditions of a share-based payment award. The amendments in this update are effective for all entities for annual periods, and interim periods within those annual periods, beginning after December 15, 2017. The Company adopted ASU No. 2017-09 in the current year with no material impact to the consolidated financial statements.

In February 2018, the FASB issued ASU No. 2018-03, Technical Corrections and Improvements to Financial Instruments — Overall (Subtopic 825-10): Recognition and Measurement of Financial Assets and Financial Liabilities, which retained the current framework for accounting for financial instruments in generally accepted accounting principles (GAAP) but made targeted improvements to address certain aspects of recognition, measurement, presentation, and disclosure of financial instruments. The amendments in this ASU are effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years beginning after June 15, 2018. The Company adopted ASU No. 2018-03 in the current year with no material impact to the consolidated financial statements.

In August 2018, the FASB issued ASU No. 2018-13 Fair Value Measurement (Topic 820) – Disclosure Framework – Changes to the Disclosure Requirements for Fair Value Measurement. The amendments affect any entity required to make disclosures about recurring or nonrecurring fair value measurements. The amendments are effective for all entities for fiscal years beginning after December 15, 2019. The Company is currently evaluating the impact of the adoption of ASU No. 2018-13 on its consolidated financial statements.

Property and Equipment, Net

12 Months Ended

Dec. 31, 2018

Property Plant And Equipment [Abstract]

Property and Equipment, Net

Note 4. Property and Equipment, Net

Property and equipment, net consisted of the following (in thousands):

	As of December 31,
	2018			2017
Laboratory equipment	$	2,348		$	2,404
Software and computer equipment		477			424
Furniture and fixtures		85			147
Vehicles		204			203
Leasehold improvements		2,082			2,002
Property and equipment, gross		5,196			5,180
Less accumulated depreciation and amortization		(4,801	)		(4,881	)
Property and equipment, net	$	395		$	299

Depreciation and amortization expense is $154,000 and $279,000 for the years ended December 31, 2018 and 2017, respectively.

Investments and Fair Value Measurements

12 Months Ended

Dec. 31, 2018

Investments And Fair Value Measurements [Abstract]

Investments and Fair Value Measurements

Note 5. Investments and Fair Value Measurements

Available-for-Sale Investments

The Company classified short-term investments as “available-for-sale.” These short-term investments are free of trading restrictions. The investments are carried at fair value, based on quoted market prices or other readily available market information. Unrealized gains and losses, net of taxes, are included in accumulated other comprehensive loss, which is reflected as a separate component of stockholder’s equity in the Consolidated Balance Sheets. Gains and losses are recognized when realized in the Consolidated Statements of Operations and Comprehensive Loss.

The following tables summarize the amortized cost and fair value of the available-for-sale investment securities portfolio at December 31, 2018 and December 31, 2017, and the corresponding amounts of unrealized gains and losses recognized in accumulated other comprehensive income:

(Dollars in thousands)	Amortized Cost		Unrealized Gains		Unrealized Losses		Estimated Fair Value
December 31, 2018
Cash equivalents:
Money market funds	$	9,902	$	—	$	—	$	9,902
Commercial paper		1,345		—		—		1,345
Short-term investments:
Corporate Securities	656			—		—		656
Treasury Bills		1,195		—		—		1,195
Commercial paper		6,776		—		—		6,776
U.S. government securities		1,198		—		—		1,198
Total Assets at Fair Value	$	21,072	$	—	$	—	$	21,072

(Dollars in thousands)	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
December 31, 2017
Cash equivalents:
Money market funds	$	8,943	$	—	$	—		$	8,943
Short-term investments:
Commercial paper		1,399		—		—		$	1,399
U.S. government securities		2,500		—		(1	)	$	2,499
Total Assets at Fair Value	$	12,842	$	—	$	(1	)	$	12,841

The Company did not have any investment categories that were in a continuous unrealized loss position for more than twelve months as of December 31, 2018. The unrealized gains and losses amounts above are included in accumulated other comprehensive income or loss

As of December 31, 2018, for fixed income securities that were in unrealized loss positions, the Company has determined that (i) it does not have the intent to sell any of these investments, and (ii) it is not more likely than not that it will be required to sell any of these investments before recovery of the entire amortized cost basis. The Company anticipates that it will recover the entire amortized cost basis of such fixed income securities and has determined that no other-than-temporary impairments associated with credit losses were required to be recognized during the year ended December 31, 2018.

Fair Value Measurement

The fair value of the available-for-sale investments at December 31, 2018 were as follows:

	Fair Value Measurements at December 31, 2018
(Dollars in thousands)	Level 1		Level 2		Level 3		Total
Assets at Fair Value
Cash equivalents:
Money market funds	$	9,902	$	—	$	—	$	9,902
Commercial paper		—		1,345				1,345
Short-term investments:
Corporate Securities		—		656				656
Treasury Bills		1,195		—				1,195
Commercial paper		—		6,776		—		6,776
U.S. government securities		1,198		—		—		1,198
Total Assets at Fair Value	$	12,295	$	8,777	$	—	$	21,072

The fair value of the available-for-sale investments at December 31, 2017 were as follows:

	Fair Value Measurements at December 31, 2017
(Dollars in thousands)	Level 1		Level 2		Level 3		Total
Assets at Fair Value
Cash equivalents:
Money market funds	$	8,943	$	—	$	—	$	8,943
Short-term investments:
Commercial Paper		—		1,399		—		1,399
U.S. government securities		2,499		—		—		2,499
Total Assets at Fair Value	$	11,442	$	1,399	$	—	$	12,841

The Company uses the market approach technique to value its financial instruments and there were no changes in valuation techniques during 2018 or 2017. The Company’s financial instruments consist primarily of cash and cash equivalents, accounts receivable, accounts payable and accrued liabilities. For accounts receivable, accounts payable and accrued liabilities, the carrying amounts of these financial instruments as of December 31, 2018 and 2017 were considered representative of their fair values due to their short term to maturity or repayment. Cash equivalents are carried at cost, which approximates their fair value.

The Company’s Level 3 liabilities, which were measured and recorded on a recurring basis, consist of liabilities related to the Purchase Agreement and the June Offering described in Note 11. The following table sets forth the establishment of these liabilities, as well as a summary of the changes in the fair value and other adjustments (in thousands):

	(Level 3)
(Dollars in thousands)	Common Stock Warrant Liability - Purchase Agreement			Common Stock Adjustment Feature Liability - Purchase Agreement			Common Stock Warrant Liability - June Offering			Total
Balance as of December 31, 2017	$	—		$	—		$	—		$	—
Common stock and warrants issued in conjunction with securities purchase agreements		10,200			3,800			9,022			23,022
Change in fair value and other adjustments		(7,846	)		4,578			(6,293	)		(9,561	)
Reclassification of common stock adjustment feature liability balance to equity		—			(8,378	)		—			(8,378	)
Balance as of December 31, 2018	$	2,354		$	—		$	2,729		$	5,083

Adoption of ASC Topic 606 "Revenue from Contracts with Customers"

12 Months Ended

Dec. 31, 2018

Revenue From Contract With Customer [Abstract]

Adoption of ASC Topic 606, Revenue from Contracts with Customers

Note 6. Adoption of ASC Topic 606, “Revenue from Contracts with Customers”

In May 2014, the FASB issued ASU No. 2014-09 (Topic 606) "Revenue from Contracts with Customers." Topic 606 supersedes the revenue recognition requirements in Topic 605 “Revenue Recognition” (Topic 605) and requires entities to recognize revenue when control of the promised goods or services is transferred to customers at an amount that reflects the consideration to which the entity expects to be entitled to in exchange for those goods or services.

On January 1, 2018, the Company adopted Topic 606 using the modified retrospective method applied to those contracts which were not completed as of January 1, 2018. Results for reporting periods beginning after January 1, 2018 are presented in accordance with Topic 606, while prior period amounts are not adjusted and continue to be reported in accordance with the Company’s historical accounting under Topic 605. With the adoption of Topic 606, tax recognition will now follow book recognition for up-front license and commercial value sharing fees. Annual license fees and milestone fees may continue to be recognized differently for book and tax to the extent that revenue recognized for book is prior to cash receipts.

The Company recorded a net reduction to its accumulated deficit of $2.4 million on January 1, 2018, with a corresponding reduction to unearned revenue, due to the cumulative impact of adopting Topic 606. The adjustment pertained to up-front license fees which were previously deferred for which the performance obligation was determined to be complete as of the date of adoption. The impact to revenues with the adoption of Topic 606 for the year ended December 31, 2018 was a decrease of $328,000 relating to the above mentioned up-front license fee revenues.

Revenues represent amounts earned from product sales, grants and contract research and license agreements. As it pertains to product sales and grants and contract research, there are no changes from Topic 605 compared to the adoption of Topic 606. There is a change in methodology from Topic 605 to Topic 606 that impacts the recognition of revenues from license agreements. The Company’s license agreements have one performance obligation and various payment terms over a long commercial development timeline ranging from approximately 10 to 20 years. These payment terms may contain, but are not limited to:

Up-front non-refundable license fees

Annual license fees

Milestone fees

Commercial value share fees

Under Topic 605, up-front license fees were deferred and amortized over the estimated commercial development timeline. Under Topic 606, such fees will be recognized upon execution of the agreement. The deferred balance remaining from the existing portfolio of license agreements that were executed prior to January 1, 2018 were recorded as a reduction to accumulated deficit upon the adoption of ASC 606 on January 1, 2018. Up-front license fees for newly executed agreements will be recognized upon execution.

Under Topic 605, annual license fees were recognized on the annual due date as such fees were not due if a milestone was met or if termination of the agreement occurred. Under Topic 606, annual license fees are variable consideration that is initially constrained and recognized only when it is probable that such amounts would not be reversed. The evaluation and analysis of such fees is performed and once an annual license fee is deemed probable to have been earned, it is recognized in full in that period.

Under Topic 605, milestone fees were recognized when the Company and partner licensee mutually agreed the milestone had been achieved. Under Topic 606, milestone fees are variable consideration that is initially constrained and recognized only when it is probable that such amounts would not be reversed. The Company assesses when achievement of milestones are probable in order to determine the timing of revenue recognition for milestone fees. Once a milestone is deemed probable to be achieved, it is recognized in full in that period.

There is no change from Topic 605 to Topic 606 pertaining to future commercial value revenue recognition. Commercial value share fees will be recognized based on subsequent sales by the licensee. The Company has not recognized any of these fees to date and does not expect to do so for several years.

Variable Interest Entity

12 Months Ended

Dec. 31, 2018

Equity Method Investments And Joint Ventures [Abstract]

Variable Interest Entity

Note 7. Variable Interest Entity

In February 2012, the Company formed Verdeca LLC (“Verdeca”), which is equally owned with Bioceres, Inc. (“Bioceres”), a U.S. wholly owned subsidiary of Bioceres, S.A., an Argentine corporation. Bioceres, S.A. is an agricultural investment and development cooperative owned by approximately 300 shareholders, including some of South America’s largest soybean growers. Verdeca was formed to develop and deregulate soybean varieties using both partners’ agricultural technologies.

Both the Company and Bioceres incur expenses in support of specific activities agreed, as defined by joint work plans, which apply fair market value to each partner’s activities. Unequal contributions of services are equalized by the partners through cash payments. Verdeca is not the primary obligor for these activities performed by the Company or Bioceres. An agreement executed in conjunction with the formation of Verdeca specified that if Bioceres determines it requires cash to fund its contributed services (subject to certain annual limits), Bioceres, S.A. may elect to sell shares of its common stock to the Company for an amount not exceeding $5.0 million in the aggregate over a four-year period. The Company determined that its commitment to purchase common stock in Bioceres, S.A. as a means to provide capital to Verdeca resulted in a de facto agency relationship between the Company and Bioceres. The Company considers qualitative factors in assessing the primary beneficiary which include understanding the purpose and design of the VIE, associated risks that the VIE creates, activities that could be directed by the Company, and the expected relative impact of those activities on the economic performance of the VIE. Based on an evaluation of these factors, the Company concluded that it is the primary beneficiary of Verdeca.

Under the terms of the joint development agreement, the Company has incurred direct expenses and allocated overhead in the amount of $947,000 and $912,000 for the years ended December 31, 2018 and 2017, respectively.

Accounts Payable and Accrued Expenses

12 Months Ended

Dec. 31, 2018

Payables And Accruals [Abstract]

Accounts Payable and Accrued Expenses

Note 8. Accounts Payable and Accrued Expenses

Accounts payable and accrued expenses consisted of the following (in thousands):

	As of December 31,
	2018		2017
Accounts payable—trade	$	285	$	366
Payroll and benefits		1,096		805
Research and development		433		899
Royalty fees due to unrelated parties		187		177
Consulting		92		32
Rent and utilities		91		51
Legal		285		83
Accrued withholding taxes		—		24
Other		176		59
Total accounts payable and accrued expenses	$	2,645	$	2,496

Exit or Disposal Activities

In 2016, the Company completed a comprehensive strategic review of its technology programs, pipeline, partner program progress, competitive landscape and market conditions, which resulted in the decision to realign its organizational capabilities to best support the Company’s near-term product commercialization needs and preserve cash. As a result, a number of personnel changes were made, including the elimination of 23 positions. The severance costs associated with this reduction in force were $192,000 for one-time employee termination benefits, and $224,000 in severance costs in connection with an executive employment contract, both of which, are recorded in Selling, General, and Administrative expense for the year ended December 31, 2016. A portion of the one-time employee termination benefits was paid out in December 2016 and the remaining severance amount of $389,000 was accrued under payroll and benefits as of December 31, 2016 and paid in 2017. Additionally, the Company closed its Seattle office in March 2017. The Company has no other associated exit or disposal costs pertaining to the years ended December 31, 2018 and 2017.

Collaborative Arrangements

12 Months Ended

Dec. 31, 2018

Organization Consolidation And Presentation Of Financial Statements [Abstract]

Collaborative Arrangements

Note 9. Collaborative Arrangements

In August 2017, the Company entered into a collaborative arrangement for the research, development and commercialization of an improved wheat quality trait in North America. This collaborative arrangement is a contractual agreement with Corteva Agriscience (“Corteva”) involves a joint operating activity where both Arcadia and Corteva are active participants in the activities of the collaboration. Arcadia and Corteva participate in the research and development, and Arcadia has the primary responsibility for the intellectual property strategy while Corteva will generally lead the marketing and commercialization efforts. Both parties are exposed to significant risks and rewards of the collaboration and the agreement includes both cost sharing and profit sharing. The activities are performed with no guarantee of either technological or commercial success.

The Company accounts for research and development (“R&D”) costs in accordance ASC 730, Research and Development, which states R&D costs must be charged to expense as incurred. Accordingly, internal R&D costs are expensed as incurred. Third-party R&D costs are expensed when the contracted work has been performed or as milestone results are achieved.

Long-Term Debt

12 Months Ended

Dec. 31, 2018

Debt Disclosure [Abstract]

Long-Term Debt

Note 10. Long-Term Debt

There was no long-term debt as of December 31, 2018 and 2017.

Term Loan

In December 2015, the Company entered into a loan and security agreement (“Term Loan”) with Silicon Valley Bank (the “Bank”) providing for a senior secured term loan facility in the amount of $25.0 million, which proceeds were used to repay all existing debt. In July 2017, the Company repaid the Term Loan with Silicon Valley Bank, along with the $625,000 end-of-term fee and $500,000 prepayment fee.

The Term Loans’ prepayment and end of term fees of $1.1 million were recorded as a loss on extinguishment of debt, along with $41,000 of deferred loan issuance fees, partially offset by $267,000 of end of term fees previously amortized, netting to a loss of $900,000. As of the payoff date, the Company was in compliance with all covenants.

The Company recognized related interest expense of $747,000 for the year ended December 31, 2017, of which $98,000 was related to the debt discount.

Private Placement and Registered Direct Offering

12 Months Ended

Dec. 31, 2018

Warrants And Rights Note Disclosure [Abstract]

Private Placement and Registered Direct Offering Disclosure

Note 11. Private Placement and Registered Direct Offering

Private Placement

On March 22, 2018, the Company issued 300,752 shares of its common stock (“Common Stock”) and warrants to purchase up to 300,752 shares of Common Stock with an initial exercise price equal to $45.75 (the “Warrants”), in a private placement (the “Private Placement”) in accordance with a securities purchase agreement (the “Purchase Agreement”) entered into with certain institutional and accredited investors (collectively, the “Purchasers”) on March 19, 2018. The Warrants are immediately exercisable, subject to certain ownership limitations, and expire five years after the date of issuance.

The per share purchase price of the Common Stock and per share exercise price for the Warrants were subject to adjustment based on the volume weighted average price for the three trading days (the “VWAP Calculation”) after each of the following: (i) the date that a registration statement covering the resale of the securities being issued in the Private Placement (“Resale Registration Statement”) has been declared effective by the SEC, (ii) if a registration statement covering all securities issued in the Private Placement is not declared effective, then the date that the securities can be sold under Rule 144 under the Securities Act of 1933, as amended, and (iii) if later than the dates set forth in item (i) and (ii), then the date that the Company’s shareholders approve the Private Placement. After each adjustment, the per share purchase price for Common Stock was automatically reduced to 80% of the VWAP Calculation, and the per share exercise price for the Warrant was automatically reduced, to 110% of the VWAP Calculation; provided, that in no event, will the per share purchase price for the Common Stock or the exercise price for the Warrants be less than $8.322. Upon any adjustment of the per share exercise price for the Warrants, then the number of shares exercisable under the Warrants would be increased so that the aggregate exercise price payable after adjustment was equal to the aggregate exercise price payable prior to such adjustment.

The Company filed the Resale Registration Statement with the SEC on March 30, 2018, and it was declared effective on April 23, 2018. As described above and based upon the applicable VWAP Calculations relating to these events, each of these events caused an adjustment to the number of shares issued in the Private Placement and underlying the Warrants. Following the effectiveness of the Resale Registration Statement, on April 23, 2018 the number of shares issued pursuant to the Purchase Agreement increased from 300,752 to 798,754, the total number of shares issuable upon exercise of the Warrants increased from 300,752 to 799,300 and the per share exercise price of the Warrants reduced from $45.75 to $17.2143. The Company held a special meeting of its shareholders on May 2, 2018 and obtained shareholder approval for the issuance of Common Stock in the Private Placement. Following shareholder approval of the issuance of shares in the Private Placement, on May 8, 2018 the number of shares issued pursuant to the Purchase Agreement increased from 798,754 to 1,201,634, the total number of shares issuable upon exercise of the Warrants increased from 799,300 to 1,282,832 and the per share exercise price of the Warrants reduced from $17.2143 to $10.7258.

The aggregate net proceeds received by the Company from the Private Placement was $8.7 million, consisting of gross proceeds of $10.0 million less offering costs of $1.3 million. The Company entered into the Private Placement to secure additional capital to strengthen its cash resources required to launch its new health and nutrition ingredient product commercialization and production scale-up plans, as well as to continue the deregulation and commercialization of its stress tolerant HB4 soybean trait. More specifically, net proceeds will be used for working capital to fund the continued introgression of quality ingredient traits into elite germ plasm, additional seed bulk-up, increased planting acreage, consumer brand development and a number of other pre-commercialization and commercialization activities.

The common stock adjustment feature and common stock warrants were determined to be liabilities based on each instrument’s adjustment features and the contingent cash payment feature of the common stock warrants. The liabilities were accounted for at their respective fair values at inception using a Monte Carlo simulation model with the following assumptions: volatility of 100 percent, stock price of $32.52 and risk-free rate of 2.63%. At inception, the fair values of the common stock adjustment feature and the common stock warrant liabilities were $3.8 million and $10.2 million, respectively. As the combined value of the liabilities exceeded the $10.0 million of proceeds, no value was assigned to the common stock issued and an initial loss of $4.0 million was recognized.

In May 2018, following the Private Placement’s final adjustment, the terms of the warrants and the number of common stock shares issuable in the private placement became known and fixed. As a result, the common stock adjustment feature liability was marked-to-market and valued at $8.4 million at May 7, 2018, resulting in an additional loss of $2.4 million recognized in the second quarter of 2018. The Company subsequently reclassified the common stock adjustment feature liability’s balance of $8.4 million to stockholders’ equity. The common stock warrant liability was marked-to-market and valued at $2.4 million at December 31, 2018, resulting in income of $7.9 million recognized throughout the year ended December 31, 2018.

Registration Rights Agreement

In connection with the Private Placement, the Company entered into a registration rights agreement (the “Registration Rights Agreement”). Pursuant to the Registration Rights Agreement, the Company filed the Resale Registration Statement with the SEC on March 30, 2018 for purposes of registering the resale of the shares of Common Stock issued pursuant to the Purchase Agreement and the shares of Common Stock issuable upon exercise of the Warrants. The SEC declared the registration statement effective on April 23, 2018.

Offering Costs

In connection with the Private Placement, the Company paid to a placement agent an aggregate fee equal to $850,000. The Company also granted warrants to purchase a total of 15,038 shares of common stock (the “Placement Agent Warrants”) that have an exercise price per share equal to $41.5625 and a term of five years. The Placement Agent Warrants were issued for services performed by the placement agent as part of the Private Placement and were treated as offering costs. The value of the Placement Agent Warrants was determined to be $526,000 using the Black-Scholes Model with input assumptions including the Company’s stock price, expected life of the warrants, stock price volatility determined from the Company’s historical stock prices and the volatility of a peer group, and the risk-free interest rate for the term of the warrants. The Company incurred additional offering costs totaling $458,000 that consist of direct incremental legal, advisory, accounting and filing fees relating to the Private Placement. The offering costs, inclusive of the Placement Agent Warrants, totaled $1.8 million was expensed in the year ended December 31, 2018.

Registered Direct Offering

On May 11, 2018, the Company filed a shelf Registration Statement on Form S-3 with the SEC which was declared effective on June 8, 2018. This shelf registration process allows the Company to sell any combination of common stock, preferred stock, warrants and units consisting of such securities in one or more offerings from time to time having an aggregate initial offering price of $50 million.

On June 11, 2018, the Company entered into agreements with several institutional and accredited investors (the “June Purchase Agreement”) for the purchase of 1,392,345 shares of its common stock at a purchase price of $9.93 per share for gross proceeds of $13.8 million (the “June Offering”). The 1,392,345 shares of common stock sold in the June Offering were issued pursuant to a prospectus, dated June 8, 2018, and a prospectus supplement dated June 11, 2018, in connection with a takedown from the Company’s shelf Registration Statement on Form S-3. The June Offering closed on June 14, 2018.

Additionally, in a concurrent private placement (the “June Private Placement”), the Company issued to the investors unregistered warrants to purchase up to 1,392,345 shares of common stock at a purchase price per warrant of $0.125, for gross proceeds of $174,000. The warrants, and the shares of common stock underlying the warrants, have not been registered with the SEC and have an exercise price of $9.94 per share. Subject to certain ownership limitations, the warrants are exercisable upon issuance and expire five and one-half years after the date of issuance.

The aggregate net proceeds received by the Company for the June Offering were $12.8 million, consisting of gross proceeds of $14.0 million less offering costs of $1.2 million. The Company intends to use the net proceeds from this offering for general corporate purposes, including, but not limited to, scale-up of its GoodWheat^TM Resistant Starch wheat production, early commercialization activities, continued research and development activities and for general and administrative expenses.

The common stock warrants were determined to be a liability as they have a contingent cash payment feature. The common stock warrants were accounted for at their fair value at inception using a Black Scholes Merton model with the following assumptions: volatility of 108 percent, stock price of $8.20 and risk-free rate of 2.83%. At inception, the fair value of the common stock warrants was $9.0 million and the remaining $5.0 million of the $14.0 million of proceeds was allocated to the common stock using the residual method and accounted for as stockholders’ equity. The common stock warrants were marked-to-market and valued at $2.7 million at December 31, 2018, resulting in income of $6.3 million recognized throughout the year ended December 31, 2018.

Offering Costs

In connection with the June Offering, the Company paid to a placement agent an aggregate fee equal to $980,000. The Company also granted warrants to purchase a total of 69,617 shares of common stock (“June Placement Agent Warrants”) that have an exercise price per share equal to $12.568 and a term of five years. The Placement Agent Warrants were issued for services performed by the placement agent as part of the June Offering and were treated as offering costs. The value of the June Placement Agent Warrants was determined to be $427,000 using the Black-Scholes Model with input assumptions including the Company’s stock price, expected life of the warrants, stock price volatility determined from the Company’s historical stock prices and the volatility of a peer group, and the risk-free interest rate for the term of the warrants. The Company incurred additional offering costs totaling $197,000 that consist of direct incremental legal, advisory, accounting and filing fees relating to the June Offering. The offering costs, inclusive of the June Placement Agent Warrants, totaled $1.6 million and allocated to the common stock warrant liability and the common stock using their relative fair values. A total of $721,000 was allocated to the common stock warrant liability for the year ended December 31, 2018. The remaining $911,000 was allocated to the common stock and offset to additional paid in capital.

Registration of Warrant Shares

On December 27, 2018, the Company filed a Registration Statement (“Form S-1”) with the SEC on December 27, 2018 to register for resale the 15,038 Placement Agent Warrants issued in connection with the Private Placement, and 1,392,345 common stock warrants and 69,617 June Placement Agent Warrants issued in connection with the June Private Placement. The Form S-1 was declared effective on February 15, 2019.

Stock-Based Compensation

12 Months Ended

Dec. 31, 2018

Disclosure Of Compensation Related Costs Share Based Payments And Warrants [Abstract]

Stock-Based Compensation and Warrants

Note 12. Stock-Based Compensation and Warrants

Stock Incentive Plans

The Company has two equity incentive plans: the 2006 Stock Plan (“2006 Plan”) and the 2015 Omnibus Equity Incentive Plan (“2015 Plan”).

In 2006, the Company adopted the 2006 Plan, which provided for the granting of stock options to executives, employees, and other service providers under terms and provisions established by the Board of Directors. The Company granted non-statutory stock options (“NSOs”) under the 2006 Plan until May 2015, when it was terminated as to future awards, although it continues to govern the terms of options that remain outstanding and were issued under the 2006 Plan. The 2015 Plan became effective upon the Company’s IPO in May 2015 and all shares that were reserved, but not issued, under the 2006 Plan were assumed by the 2015 Plan. Upon effectiveness, the 2015 Plan had 154,387 shares of common stock reserved for future issuance, which included 10,637 that were transferred to and assumed by the 2015 Plan. The 2015 Plan provides for automatic annual increases in shares available for grant. In addition, shares subject to awards under the 2006 Plan that are forfeited or canceled will be added to the 2015 Plan. The 2015 Plan provides for the grant of incentive stock options (“ISOs”), NSOs, restricted stock awards, stock units, stock appreciation rights, and other forms of equity compensation, all of which may be granted to employees, officers, non-employee directors, and consultants. The ISOs and NSOs will be granted at a price per share not less than the fair value at the date of grant. Options granted generally vest over a four-year period, with 25% vesting at the end of one year and the remaining vesting monthly thereafter; however, the options granted in the third quarter of 2018 vest over a two-year period, vesting monthly on a pro-rated basis. Options granted, once vested, are generally exercisable for up to 10 years, after grant.

As of December 31, 2018, a total of 494,191 shares of common stock were reserved for issuance under the 2015 Plan, of which 26,349 shares of common stock are available for future grant. As of December 31, 2018, a total of 62,202 and 467,842 options are outstanding under the 2006 and 2015 Plans, respectively.

The following is a summary of stock option information and weighted average exercise prices under the Company’s stock incentive plans (in thousands, except share data and price per share):

	Shares Subject to Outstanding Options			Weighted- Average Exercise Price Per Share		Aggregate Intrinsic Value
Outstanding — Balance at December 31, 2016		228,939		$	87.60	$	—
Options granted		111,336			9.20
Options exercised		—			—
Options forfeited		(24,334	)		31.75
Options expired		(27,812	)		98.95
Outstanding — Balance at December 31, 2017		288,129			63.62	$	—
Options granted		302,077			6.65
Options exercised		(44,354	)		21.73
Options forfeited		(4,006	)		14.21
Options expired		(11,802	)		43.73
Outstanding — Balance at December 31, 2018		530,044			35.53	$	—
Vested and expected to vest — December 31, 2018		519,655			35.91	$	—
Exercisable —December 31, 2018		183,300		$	71.47	$	—

Aggregate intrinsic value represents the difference between the exercise price of the options and the estimated fair value of the Company’s common stock determined by our Board of Directors for each of the respective periods. The intrinsic value of options exercised was $0 for the years ended December 31, 2017 and 2018.

At December 31, 2018 and 2017, the total grant-date fair value of shares vested during the years was $1.3 million and $449,000, respectively.

As of December 31, 2018, there was $1.2 million of unrecognized compensation cost related to unvested stock-based compensation grants that will be recognized over the weighted-average remaining recognition period of 2.1 years.

In determining the fair value of the stock-based awards, the Company uses the Black-Scholes option-pricing model and assumptions discussed below. Each of these inputs is subjective and generally requires significant judgment to determine.

Expected Term—The expected term is the estimated period of time outstanding for stock options granted and was estimated based on historical, as well as anticipated future, exercise activity.

Expected Volatility—Since the Company was privately held and does not have a long trading history for its common stock, the expected volatility was estimated based on the average volatility for comparable publicly traded biotechnology companies over a period equal to the expected term of the stock option grants. When selecting comparable publicly traded biotechnology companies on which it has based its expected stock price volatility, the Company selected companies with comparable characteristics to it, including enterprise value, risk profiles, position within the industry, and with historical share price information sufficient to meet the expected life of the stock-based awards. The historical volatility data was computed using the daily closing prices for the selected companies’ shares during the equivalent period of the calculated expected term of the stock-based awards. The Company will continue to apply this process until a sufficient amount of historical information regarding the volatility of its own stock price becomes available.

Risk-Free Interest Rate—The risk-free interest rate is based on the interest rate of U.S. Treasuries of comparable maturities on the date the options were granted.

Expected Dividend—The expected dividend yield is based on the Company’s expectation of future dividend payouts to common stockholders.

The fair value of stock option awards to employees was estimated at the date of grant using a Black-Scholes option-pricing model with the following weighted-average assumption:

	Year Ended December 31,
Assumptions	2018		2017
Expected term (years)		5.99		6.12
Expected volatility	99%		79%
Risk-free interest rate	2.95%		1.90%
Expected dividend yield		—		—

The weighted- average, estimated grant date fair value of employee stock options granted during the years ended December 31, 2018 and 2017 was $6.65 and $9.20, respectively. The Company recognized $1.6 million and 1.5 million of compensation expense for stock options to employees and board members for the years ended December 31, 2018 and 2017, respectively.

Employee Stock Purchase Plan

The Company’s 2015 Employee Stock Purchase Plan (“ESPP”) became effective on May 14, 2015. The ESPP allows eligible employees to purchase shares of the Company’s common stock at a discount of up to 15% of their eligible compensation through payroll deductions, subject to any plan limitations. After the first offering period, which began on May 14, 2015 and ended on February 1, 2016, the ESPP provides for six-month offering periods, and at the end of each offering period, employees are able to purchase shares at 85% of the lower of the fair market value of the Company’s common stock on the first trading day of the offering period or on the last day of the offering period. As of December 31, 2018, the number of shares of common stock reserved for future issuance under the ESPP is 89,489. The ESPP provides for automatic annual increases in the shares available for purchase beginning on January 1, 2016. As of December 31, 2018, 6,853 shares had been issued under the ESPP. The Company recorded $11,000 and $13,000 of ESPP related compensation expense for the years ended December 31, 2018 and 2017, respectively.

Warrants

As of December 31, 2018, the Company had 2,822,903 common stock warrants outstanding with a weighted average exercise price of $18.37. The expiration of the warrants ranges from March 2019 to June 2023.

On December 2013, the Company issued warrants to Mahyco International to purchase 3,784 shares of common stock, exercisable as of the issuance date, at an exercise price of $330.40 per share. These warrants expired on December 11, 2018.

In connection with the Series D preferred stock financing in the first half of 2014, the Company issued warrants, exercisable as of the issuance date, to the Series D preferred stock investors to purchase an aggregate of 61,397 shares of common stock at an exercise price of $363.20 per share and to the placement agents to purchase 1,674 shares of common stock at $268.80. The warrants expire five years from the issuance date.

As of December 31, 2018, 1,297,870 common stock warrants are outstanding that were issued in the June Private Placement. The final exercise price for these warrants is $10.7258 as adjusted in accordance with the Purchase Agreement’s adjustment provisions. See Note 11.

As of December 31, 2018, 1,461,962 common stock warrants are outstanding in accordance with the June Offering. Of the total, 1,392,345 shares have a purchase price of $9.94 and the remaining 69,617 common stock warrants have an exercise price of $12.568. See Note 11.

Commitment and Contingencies

12 Months Ended

Dec. 31, 2018

Commitments And Contingencies Disclosure [Abstract]

Commitments and Contingencies

Note 13. Commitments and Contingencies

Leases

The Company leases office and laboratory space, greenhouse space, grain storage bins, warehouse space, and equipment under operating lease agreements having initial lease terms ranging from one to five years, including certain renewal options available to the Company at market rates. The Company also leases land for field trials on a short-term basis. Future minimum payments under non-cancelable operating leases in effect as of December 31, 2018, are presented below (in thousands):

Years Ending December 31,	Amounts
2019		704
2020		713
2021		595
2022		497
2023		295
Total future minimum payments under non- cancelable operating leases	$	2,804

Rent expense under all operating leases totaled $1.3 and $1.2 million for years ended December 31, 2018 and 2017, respectively.

Legal Matters

From time to time, in the ordinary course of business, the Company may become involved in certain legal proceedings. Except as discussed in Item 3, we currently are not a party to any material legal proceedings.

Contingent Liability Related to the Anawah Acquisition

On June 15, 2005, the Company completed its agreement and plan of merger and reorganization with Anawah, Inc. (“Anawah”), to purchase the Anawah’s food and agricultural research company through a non-cash stock purchase. Pursuant to the merger with Anawah, and in accordance with the ASC 805 - Business Combinations, the Company incurred a contingent liability not to exceed $5.0 million. This liability represents amounts to be paid to Anawah’s previous stockholders for cash collected on revenue recognized by the Company upon commercial sale of certain specific products developed using technology acquired in the purchase. As of December 31, 2010, the Company ceased activities relating to three of the six Anawah product programs thus, the contingent liability was reduced to $3.0 million. During the third quarter of 2016, one of the programs previously accrued for was abandoned and another program previously abandoned was reactivated. As of December 31, 2018, the Company continues to pursue a total of three development programs using this technology and believes that the contingent liability is probable. As a result, $3.0 million remains on the Consolidated Balance Sheet as an other noncurrent liability.

Contracts

The Company has entered into contract research agreements with unrelated parties that require the Company to pay certain funding commitments. The initial terms of these agreements range from one to three years in duration and in certain cases are cancelable.

The Company licenses certain technologies via executed agreements (“In-Licensing Agreements”) that are used to develop and advance the Company’s own technologies. The Company has entered into various In-Licensing Agreements with related and unrelated parties that require the Company to pay certain license fees, royalties, and/or milestone fees. In addition, certain royalty payments ranging from 2% to 15% of net revenue amounts as defined in the In-Licensing Agreements will be due.

Royalties due to both related and unrelated parties on license revenue accrued as of December 31, 2018 and 2017 were $216,000 and $206,000, respectively. Royalties are included within research and development on the Consolidated Statements of Operations and Comprehensive Loss.

Milestone payments are contingent upon the successful development or implementation of various technologies. Payments for milestones yet to be achieved totaled $2.0 million each year for the years ended December 31, 2018 and 2017. The timing of the payments is not determinable at this time pending research and development currently in progress; however, no significant payments were made during the years ended December 31, 2018 and 2017.

The Company could be adversely affected by certain actions by the government as it relates to government contract revenue received in prior years. Government agencies, such as the Defense Contract Audit Agency routinely audit and investigate government contractors. These agencies review a contractor’s performance under its agreements; cost structure; and compliance with applicable laws, regulations and standards. The agencies also review the adequacy of, and a contractor’s compliance with, its internal control systems and policies, including the contractor’s purchasing, property, estimating, compensation and management information systems. While the Company’s management anticipates no adverse result from an audit, should any costs be found to be improperly allocated to a government agreement, such costs will not be reimbursed, or if already reimbursed, may need to be refunded. If an audit uncovers improper or illegal activities, civil and criminal penalties and administrative sanctions, including termination of contracts, forfeiture of profits, suspension of payments or fines, and suspension or prohibition from doing business with the government could occur. In addition, serious reputational harm or significant adverse financial effects could occur if allegations of impropriety were made against the Company. There currently are routine audits in process relating to government grant revenues.

Leases

12 Months Ended

Dec. 31, 2018

Lessee Disclosure [Abstract]

Leases

Note 14. Leases

The Company adopted the new lease accounting standards (Topic 842) on January 1, 2019 and used the effective date as our initial application. The Company used the modified retrospective approach, applying the new standard to all leases existing as of the date of initial application. Consequently, financial information will not be updated, and the disclosures required under the new standard will not be provided for the dates and periods before January 1, 2019. On January 1, 2019, the Company will recognize a ROU asset of $2.3 million and an operating lease liability of $2.4 million.

The new standard also provides practical expedients for an entity’s ongoing accounting. The Company has elected the short-term lease recognition exemption for field trial lease agreements. This means, for those leases that qualify, the Company will not recognize ROU assets or lease liabilities. The Company has elected the practical expedient to not separate lease and non-lease components for all of leases.

Income Taxes

12 Months Ended

Dec. 31, 2018

Income Tax Disclosure [Abstract]

Income Taxes

Note 15. Income Taxes

The components of loss before income taxes are as follows (in thousands):

	Year Ended December 31,
	2018			2017
Domestic	$	(13,470	)	$	(15,681	)
Foreign		—			—
Loss before income taxes	$	(13,470	)	$	(15,681	)

The total income tax expense for the years ended December 31, 2018 and 2017 was $10,000 and $26,000, respectively, and is comprised of current state taxes and foreign taxes withheld by governmental agencies outside of the United States, as follows (in thousands):

	Year Ended December 31,
	2018		2017
Current:
Federal	$	—	$	—
State		1		2
Foreign		9		24
Total current tax expense		10		26
Deferred:
Federal		—		—
State		—		—
Foreign		—		—
Total deferred tax benefit		—		—
Total tax expense	$	10	$	26

The Company operates in only one federal jurisdiction, the United States. The following is a reconciliation of the statutory federal income tax rate to the Company’s effective tax rate is as follows:

	Year Ended December 31,
	2018			2017
Expected income tax provision at the federal statutory rate		21.0	%		34.0	%
State taxes, net of federal benefit		8.5	%		2.6	%
Change in valuation allowance		(27.3	)%		91.4	%
Transaction costs		(2.9	)%		—
Related offering costs		(1.1	)%		—
Excess windfall benefit		1.4	%		—
Nondeductible expenses		—			0.1	%
Impact of change in federal tax rate		—			(124.6	)%
Withholding taxes		(0.1	)%		(0.2	)%
Other		0.4	%		(3.5	)%
Income tax provision		(0.1	)%		(0.2	)%

Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes, net operating loss carryforwards (“NOLs”) and other tax credits. Significant components of the Company’s deferred tax assets and liabilities are as follows (in thousands):

	As of December 31,
	2018			2017
Deferred tax assets:
Net operating loss carryforwards	$	42,097		$	37,498
Unearned revenue		26			783
Stock-based compensation		2,855			2,273
Accrued payroll and benefits		255			51
Research and development credits		171			171
Fixed asset basis difference		114			128
Inventory reserve		508			396
Charitable contributions		3			3
Total deferred tax assets		46,029			41,303
Deferred tax liabilities:
Common stock warrant liabilities		(1,529	)		—
Total deferred tax liabilities		(1,529	)		—
Less valuation allowance		(44,500	)		(41,303	)
Net deferred tax assets	$	—		$	—

Realization of the deferred tax assets is dependent upon future taxable income, if any, the amount and timing of which are uncertain. Accordingly, the net deferred tax assets have been offset by a valuation allowance. The net valuation allowance increased by $3.2 million and decreased by $14.3 million during the years ended December 31, 2018 and 2017, respectively.

On December 22, 2017, the Tax Cuts and Jobs Act (the “Tax Act”) was signed into law making significant changes to the Internal Revenue Code. Changes include, but are not limited to, a corporate tax rate decrease from 35% to 21%, effective for tax years beginning after December 31, 2017. We use the asset and liability method of accounting for income taxes. Under this method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax basis. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to reverse. As a result of the reduction in the U.S. corporate income tax rate from 35% to 21% under the Tax Act, we revalued our ending net deferred tax assets at December 31, 2017, which were fully offset by a valuation allowance. The Company considers the accounting for the Tax Act to be complete.

At December 31, 2018, the Company had federal and state NOLs aggregating approximately $168.6 million and $123.2 million, respectively. At December 31, 2018, the utilization of a portion of our NOLs is subject to an annual limitation under Section 382 of the Internal Revenue Code (IRC). Of the $168.6 million generated, $7.2 million was previously determined as unavailable to be utilized within the carryforward period. Further, the Company may have experienced an ownership change under IRC Section 382 as a result of the common shares issued in connection with the Purchase Agreement in March 2018 or in the June Offering. Such an ownership change could limit the Company’s ability to utilize its NOL carryforwards prior to expiration but would not impact the net deferred tax asset recorded given the full valuation allowance. If not utilized, these federal NOLs will begin to expire in 2020 and state NOLs will begin to expire in 2024. IRC Section 382 may also limit NOLs generated in future years.

The Company evaluates deferred tax assets, including the benefit from NOLs, to determine if a valuation allowance is required. Such evaluation is based on consideration of all available evidence using a “more likely than not” standard with significant weight being given to evidence that can be objectively verified. This assessment considers, among other matters, the nature, frequency, and severity of current and cumulative losses; forecasts of future profitability; the length of statutory carryforward periods; the Company’s experience with operating losses; and tax-planning alternatives. The significant piece of objective negative evidence evaluated was the cumulative loss incurred through the year ended December 31, 2018. Given this evidence and the expectation to incur operating losses in the foreseeable future, a full valuation allowance has been recorded against the net deferred tax asset. The Company will continue to maintain a full valuation allowance against the entire amount of its net deferred tax asset, until such time as the Company has determined that the weight of the objectively verifiable positive evidence exceeds that of the negative evidence and it is likely that the Company will be able to utilize all of its net deferred tax asset relating to its federal and state NOL carryforwards. Although the Company has established a full valuation allowance on its net deferred tax asset, for Federal tax losses before 2018 and for all state tax losses, it has not forfeited the right to carryforward tax losses up to 20 years and apply such tax losses against taxable income in such years, thereby reducing its future tax obligations. Federal tax losses generated in 2018 and later do not expire. The Company is subject to taxation in the United States and various state jurisdictions. As of December 31, 2018, the Company’s tax years for 2000 through 2018 are generally subject to examination by the tax authorities. The years are open back to 2000 to the extent the NOLs being carried forward were generated then.

The Company applies the provisions of ASC 740 related to accounting for uncertain tax positions and concluded there were no such positions associated with the Company requiring accrual of a liability. As of December 31, 2018, the Company has not accrued for any such positions. The Company is currently not under audit for federal or state tax purposes. The Company does not expect a significant change to occur within the next 12 months.

Segment Reporting

12 Months Ended

Dec. 31, 2018

Segment Reporting [Abstract]

Segment and Geographic Information

Note 17. Segment and Geographic Information

Management has determined that it has one business activity and operates in one segment as it only reports financial information on an aggregate and consolidated basis to its Chief Executive Officer, who is the Company’s chief operating decision maker.

Revenues based on the location of the customers, are as follows (in thousands):

	Year Ended December 31,
	2018		2017
United States	$	1,168	$	1,588
India		90		1,064
Africa		115		315
France		—		220
Canada		91		181
China		—		586
Belgium		—		72
Total	$	1,464	$	4,026

Net Loss per Share

12 Months Ended

Dec. 31, 2018

Earnings Per Share [Abstract]

Net Loss per Share

Note 18. Net Loss per Share

Basic net loss per share is calculated by dividing net loss attributable to common stockholders by the weightedaverage number of common shares outstanding during the period and excludes any dilutive effects of stockbased awards and warrants. Diluted net loss per share attributable to common stockholders is computed giving effect to all potentially dilutive common shares, including common stock issuable upon exercise of stock options and warrants. As the Company had net losses for the years ended December 31, 2018 and 2017, all potentially dilutive common shares were determined to be antidilutive.

Securities that were not included in the diluted per share calculations because they would be antidilutive were as follows (in shares):

	Year Ended December 31,
	2018		2017
Options to purchase common stock		530,044		288,129
Warrants to purchase common stock		2,822,903		66,845
Total		3,352,947		354,974

Related Party Transactions

12 Months Ended

Dec. 31, 2018

Related Party Transactions

Note 19. Related Party Transactions

The Company’s related parties include Moral Compass Corporation (“MCC”) and the John Sperling Foundation (“JSF”). The rights to the intellectual property owned by Blue Horse Labs, Inc. (“BHL”) were assigned to its sole shareholder, the John Sperling Revocable Trust (“JSRT”) due to BHL’s dissolution and then subsequently to the JSF. The JSF is deemed a related party of the Company because MCC, the Company’s largest stockholder, and the JSF share common officers and directors.

Transactions with related parties are reflected in the consolidated financial statements under amounts due to related parties. Outlined below are details of agreements between the Company and its related parties:

JSF receives a single digit royalty from the Company when revenue has been collected on product sales or for license payments from third parties that involve certain intellectual property developed under research funding originally from BH. Royalty fees due to JSF were $29,000 and to JSRT $29,000 as of December 31, 2018 and December 31, 2017 and are included in the Consolidated Balance Sheets as amounts due to related parties.

Summary of Significant Accounting Policies (Policies)

12 Months Ended

Dec. 31, 2018

Organization

Reverse Stock Split

Liquidity, Capital Resources, and Going Concern

Basis of Presentation and Principles of Consolidation

Use of Estimates

Cash and Cash Equivalents

Investments in Equity and Debt Securities

Other-than-Temporary Impairments on Investment

Accounts Receivable

SONOVA® Gamma Linolenic Acid (“GLA”) Safflower Oil Inventory

	As of December 31,
	2018		2017
Raw Materials	$	41	$	45
Finished Goods		886		1,352
Inventories	$	927	$	1,397

Property and Equipment

Property and equipment acquisitions are recorded at cost. Provisions for depreciation are calculated using the straight-line method over the following average estimated useful lives of the assets:

	Years
Laboratory equipment	5
Software and computer equipment	3
Furniture and fixtures	7
Vehicles	5
Leasehold improvements	2-10	*

*	Leasehold improvements are depreciated over the shorter of the estimated life of the asset or the remaining life of the lease.

Impairment of Long-Lived Assets

Fair Value of Financial Instruments

•

Level 1 inputs are quoted prices (unadjusted) in active markets for identical assets or liabilities that the Company can access at the measurement date.

•

Level 3 inputs are unobservable inputs for the asset or liability.

Concentration of Risk

Customer Concentration

Significant customers are those that represent greater than 10% of the Company’s total revenues or gross accounts receivable balance at each respective balance sheet date.

Customers representing greater than 10% of accounts receivable were as follows (in percentages):

	As of December 31,
	2018		2017
Customer A		—		18
Customer D		—		53
Customer E		—		24
Customer I		44		—
Customer M		34		1

Customers representing greater than 10% of total revenues were as follows (in percentages):

	For Year Ended December 31,
	2018		2017
Customer A		—		26
Customer D		19		18
Customer L		16		9
Customer I		13		2
Customer M		11		2
Customer K		—		14

Stock-Based Compensation

Income Taxes

Net Loss per Share

Revenue Recognition

We derive our revenues from product revenues, licensing agreements, contract research agreements, and government grants.

Unearned Revenue

The Company defers revenue to the extent that cash received in conjunction with a license agreement, contract or grant exceeds the revenue recognized in accordance with Company policies.

Cost of Product Revenues

Research and Development Expenses

Change in the Estimated Fair Value of Common Stock Warrant Liabilities and Common Stock Adjustment Feature Liability

Product Revenues

Revenue Recognition

Product Revenues

Our product revenues to date have consisted solely of sales of our SONOVA products. We generally recognize revenue from product sales upon sale to our third-party distributors or customers.

License Revenues

Revenue Recognition

License Revenues

Contract Research Revenues

Revenue Recognition

Contract Research Revenues

Government Grant Revenues

Revenue Recognition

Government Grant Revenues

Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2018

Accounting Policies [Line Items]

Summary of Inventories

Inventories consist of the following (in thousands):

	As of December 31,
	2018		2017
Raw Materials	$	41	$	45
Finished Goods		886		1,352
Inventories	$	927	$	1,397

Summary of Average Estimated Useful Lives of Assets

Provisions for depreciation are calculated using the straight-line method over the following average estimated useful lives of the assets:

	Years
Laboratory equipment	5
Software and computer equipment	3
Furniture and fixtures	7
Vehicles	5
Leasehold improvements	2-10	*

*	Leasehold improvements are depreciated over the shorter of the estimated life of the asset or the remaining life of the lease.

Customer Concentration Risk [Member]

Accounting Policies [Line Items]

Summary of Customer Concentration

Customers representing greater than 10% of accounts receivable were as follows (in percentages):

	As of December 31,
	2018		2017
Customer A		—		18
Customer D		—		53
Customer E		—		24
Customer I		44		—
Customer M		34		1

Customers representing greater than 10% of total revenues were as follows (in percentages):

	For Year Ended December 31,
	2018		2017
Customer A		—		26
Customer D		19		18
Customer L		16		9
Customer I		13		2
Customer M		11		2
Customer K		—		14

Property and Equipment, Net (Tables)

12 Months Ended

Dec. 31, 2018

Property Plant And Equipment [Abstract]

Summary of Property and Equipment, Net

Property and equipment, net consisted of the following (in thousands):

	As of December 31,
	2018			2017
Laboratory equipment	$	2,348		$	2,404
Software and computer equipment		477			424
Furniture and fixtures		85			147
Vehicles		204			203
Leasehold improvements		2,082			2,002
Property and equipment, gross		5,196			5,180
Less accumulated depreciation and amortization		(4,801	)		(4,881	)
Property and equipment, net	$	395		$	299

Investments and Fair Value Measurements (Tables)

12 Months Ended

Dec. 31, 2018

Investments And Fair Value Measurements [Abstract]

Summary of Amortized Cost and Fair Value of the Available-For-Sale Investment Securities Portfolio

(Dollars in thousands)	Amortized Cost		Unrealized Gains		Unrealized Losses		Estimated Fair Value
December 31, 2018
Cash equivalents:
Money market funds	$	9,902	$	—	$	—	$	9,902
Commercial paper		1,345		—		—		1,345
Short-term investments:
Corporate Securities	656			—		—		656
Treasury Bills		1,195		—		—		1,195
Commercial paper		6,776		—		—		6,776
U.S. government securities		1,198		—		—		1,198
Total Assets at Fair Value	$	21,072	$	—	$	—	$	21,072

(Dollars in thousands)	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
December 31, 2017
Cash equivalents:
Money market funds	$	8,943	$	—	$	—		$	8,943
Short-term investments:
Commercial paper		1,399		—		—		$	1,399
U.S. government securities		2,500		—		(1	)	$	2,499
Total Assets at Fair Value	$	12,842	$	—	$	(1	)	$	12,841

Summary of Fair Value of Available-for-Sale Investments

The fair value of the available-for-sale investments at December 31, 2018 were as follows:

	Fair Value Measurements at December 31, 2018
(Dollars in thousands)	Level 1		Level 2		Level 3		Total
Assets at Fair Value
Cash equivalents:
Money market funds	$	9,902	$	—	$	—	$	9,902
Commercial paper		—		1,345				1,345
Short-term investments:
Corporate Securities		—		656				656
Treasury Bills		1,195		—				1,195
Commercial paper		—		6,776		—		6,776
U.S. government securities		1,198		—		—		1,198
Total Assets at Fair Value	$	12,295	$	8,777	$	—	$	21,072

The fair value of the available-for-sale investments at December 31, 2017 were as follows:

	Fair Value Measurements at December 31, 2017
(Dollars in thousands)	Level 1		Level 2		Level 3		Total
Assets at Fair Value
Cash equivalents:
Money market funds	$	8,943	$	—	$	—	$	8,943
Short-term investments:
Commercial Paper		—		1,399		—		1,399
U.S. government securities		2,499		—		—		2,499
Total Assets at Fair Value	$	11,442	$	1,399	$	—	$	12,841

Summary of Changes in Fair Value and Other Adjustments of Liabilities

The following table sets forth the establishment of these liabilities, as well as a summary of the changes in the fair value and other adjustments (in thousands):

	(Level 3)
(Dollars in thousands)	Common Stock Warrant Liability - Purchase Agreement			Common Stock Adjustment Feature Liability - Purchase Agreement			Common Stock Warrant Liability - June Offering			Total
Balance as of December 31, 2017	$	—		$	—		$	—		$	—
Common stock and warrants issued in conjunction with securities purchase agreements		10,200			3,800			9,022			23,022
Change in fair value and other adjustments		(7,846	)		4,578			(6,293	)		(9,561	)
Reclassification of common stock adjustment feature liability balance to equity		—			(8,378	)		—			(8,378	)
Balance as of December 31, 2018	$	2,354		$	—		$	2,729		$	5,083

- Definition

Tabular disclosure of financial instruments measured at fair value, including those classified in shareholders' equity measured on a recurring or nonrecurring basis. Disclosures include, but are not limited to, fair value measurements recorded and the reasons for the measurements, level within the fair value hierarchy in which the fair value measurements are categorized and transfers between levels 1 and 2. Nonrecurring fair value measurements are those that are required or permitted in the statement of financial position in particular circumstances.

+ References + Details

Accounts Payable and Accrued Expenses (Tables)

12 Months Ended

Dec. 31, 2018

Payables And Accruals [Abstract]

Summary of Accounts Payable and Accrued Expenses

Accounts payable and accrued expenses consisted of the following (in thousands):

	As of December 31,
	2018		2017
Accounts payable—trade	$	285	$	366
Payroll and benefits		1,096		805
Research and development		433		899
Royalty fees due to unrelated parties		187		177
Consulting		92		32
Rent and utilities		91		51
Legal		285		83
Accrued withholding taxes		—		24
Other		176		59
Total accounts payable and accrued expenses	$	2,645	$	2,496

Stock-Based Compensation and Warrants (Tables)

12 Months Ended

Dec. 31, 2018

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Activity Under Stock Incentive Plans

The following is a summary of stock option information and weighted average exercise prices under the Company’s stock incentive plans (in thousands, except share data and price per share):

	Shares Subject to Outstanding Options			Weighted- Average Exercise Price Per Share		Aggregate Intrinsic Value
Outstanding — Balance at December 31, 2016		228,939		$	87.60	$	—
Options granted		111,336			9.20
Options exercised		—			—
Options forfeited		(24,334	)		31.75
Options expired		(27,812	)		98.95
Outstanding — Balance at December 31, 2017		288,129			63.62	$	—
Options granted		302,077			6.65
Options exercised		(44,354	)		21.73
Options forfeited		(4,006	)		14.21
Options expired		(11,802	)		43.73
Outstanding — Balance at December 31, 2018		530,044			35.53	$	—
Vested and expected to vest — December 31, 2018		519,655			35.91	$	—
Exercisable —December 31, 2018		183,300		$	71.47	$	—

Weighted-Average Fair Value Assumption of Stock Option Awards

The fair value of stock option awards to employees was estimated at the date of grant using a Black-Scholes option-pricing model with the following weighted-average assumption:

	Year Ended December 31,
Assumptions	2018		2017
Expected term (years)		5.99		6.12
Expected volatility	99%		79%
Risk-free interest rate	2.95%		1.90%
Expected dividend yield		—		—

Commitment and Contingencies (Tables)

12 Months Ended

Dec. 31, 2018

Commitments And Contingencies Disclosure [Abstract]

Schedule of Future Minimum Payments Under Non-Cancelable Operating Leases

Future minimum payments under non-cancelable operating leases in effect as of December 31, 2018, are presented below (in thousands):

Years Ending December 31,	Amounts
2019		704
2020		713
2021		595
2022		497
2023		295
Total future minimum payments under non- cancelable operating leases	$	2,804

Income Taxes (Tables)

12 Months Ended

Dec. 31, 2018

Income Tax Disclosure [Abstract]

Components of Loss Before Income Taxes

The components of loss before income taxes are as follows (in thousands):

	Year Ended December 31,
	2018			2017
Domestic	$	(13,470	)	$	(15,681	)
Foreign		—			—
Loss before income taxes	$	(13,470	)	$	(15,681	)

Schedule of Income Tax Expense Comprised of Current State Taxes and Foreign Taxes

	Year Ended December 31,
	2018		2017
Current:
Federal	$	—	$	—
State		1		2
Foreign		9		24
Total current tax expense		10		26
Deferred:
Federal		—		—
State		—		—
Foreign		—		—
Total deferred tax benefit		—		—
Total tax expense	$	10	$	26

Reconciliation of the Statutory Federal Income Tax Rate

The following is a reconciliation of the statutory federal income tax rate to the Company’s effective tax rate is as follows:

	Year Ended December 31,
	2018			2017
Expected income tax provision at the federal statutory rate		21.0	%		34.0	%
State taxes, net of federal benefit		8.5	%		2.6	%
Change in valuation allowance		(27.3	)%		91.4	%
Transaction costs		(2.9	)%		—
Related offering costs		(1.1	)%		—
Excess windfall benefit		1.4	%		—
Nondeductible expenses		—			0.1	%
Impact of change in federal tax rate		—			(124.6	)%
Withholding taxes		(0.1	)%		(0.2	)%
Other		0.4	%		(3.5	)%
Income tax provision		(0.1	)%		(0.2	)%

Deferred Tax Assets and Liabilities

Significant components of the Company’s deferred tax assets and liabilities are as follows (in thousands)

	As of December 31,
	2018			2017
Deferred tax assets:
Net operating loss carryforwards	$	42,097		$	37,498
Unearned revenue		26			783
Stock-based compensation		2,855			2,273
Accrued payroll and benefits		255			51
Research and development credits		171			171
Fixed asset basis difference		114			128
Inventory reserve		508			396
Charitable contributions		3			3
Total deferred tax assets		46,029			41,303
Deferred tax liabilities:
Common stock warrant liabilities		(1,529	)		—
Total deferred tax liabilities		(1,529	)		—
Less valuation allowance		(44,500	)		(41,303	)
Net deferred tax assets	$	—		$	—

Segment Reporting (Tables)

12 Months Ended

Dec. 31, 2018

Segment Reporting [Abstract]

Summary of Revenues Based on Location of Customers

Revenues based on the location of the customers, are as follows (in thousands):

	Year Ended December 31,
	2018		2017
United States	$	1,168	$	1,588
India		90		1,064
Africa		115		315
France		—		220
Canada		91		181
China		—		586
Belgium		—		72
Total	$	1,464	$	4,026

Net Loss per Share (Tables)

12 Months Ended

Dec. 31, 2018

Earnings Per Share [Abstract]

Schedule of Securities Not Included in Diluted per Share Calculations

Securities that were not included in the diluted per share calculations because they would be antidilutive were as follows (in shares):

	Year Ended December 31,
	2018		2017
Options to purchase common stock		530,044		288,129
Warrants to purchase common stock		2,822,903		66,845
Total		3,352,947		354,974

Description of Business - Additional Information (Detail) $ in Thousands	12 Months Ended
	Dec. 31, 2018 USD ($) shares	Dec. 31, 2017 USD ($) shares	Dec. 31, 2016 USD ($)
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Place of incorporation	Arizona
Year of incorporation	2002
Place of reincorporation	Delaware
Date of reincorporation	2015-03
Reverse split of issued and outstanding common stock	1:20
Stock split conversion ratio	0.05
Common stock, authorized \| shares	150,000,000	150,000,000
Accumulated deficit	$ 178,366	$ 167,257
Cash and cash equivalents	11,998	9,125	$ 2,013
Short-term investments	9,825	3,898
Net losses	(13,480)	(15,707)
Net cash used in operations	$ (13,631)	$ (13,965)

Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)		12 Months Ended
	Mar. 31, 2017	Dec. 31, 2018	Dec. 31, 2017
Accounting Policies [Line Items]
Reserved for doubtful accounts		$ 0	$ 0
Write-down of inventory		310,000	0
Impairment of long-lived assets		$ 0	0
Maximum [Member]
Accounting Policies [Line Items]
Cost method investment ownership percentage		20.00%
Revenue generation period		18 months
Minimum [Member]
Accounting Policies [Line Items]
Revenue generation period		9 months
Limagrain Cereal Seeds LLC [Member]
Accounting Policies [Line Items]
Common stock shares retired using cost method as result of transfer of membership interest	92,194
Impairment of equity method investments		$ 0	0
Verdeca LLC [Member]
Accounting Policies [Line Items]
VIEs Operations		0	0
VIEs assets or liabilities		$ 0	$ 0

Summary of Significant Accounting Policies - Summary of Average Estimated Useful Lives of Assets (Detail)	12 Months Ended
	Dec. 31, 2018
Laboratory equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, estimated useful lives	5 years
Software and computer equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, estimated useful lives	3 years
Furniture and fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, estimated useful lives	7 years
Vehicles [Member]
Property Plant And Equipment [Line Items]
Property and equipment, estimated useful lives	5 years
Leasehold improvements [Member] \| Minimum [Member]
Property Plant And Equipment [Line Items]
Property and equipment, estimated useful lives	2 years
Leasehold improvements [Member] \| Maximum [Member]
Property Plant And Equipment [Line Items]
Property and equipment, estimated useful lives	10 years

Summary of Significant Accounting Policies - Summary of Customer Concentration (Detail) - Customer Concentration Risk [Member]	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Accounts Receivable [Member] \| Customer A [Member]
Concentration Risk [Line Items]
Concentration risk percentage		18.00%
Accounts Receivable [Member] \| Customer D [Member]
Concentration Risk [Line Items]
Concentration risk percentage		53.00%
Accounts Receivable [Member] \| Customer E [Member]
Concentration Risk [Line Items]
Concentration risk percentage		24.00%
Accounts Receivable [Member] \| Customer I [Member]
Concentration Risk [Line Items]
Concentration risk percentage	44.00%
Accounts Receivable [Member] \| Customer M [Member]
Concentration Risk [Line Items]
Concentration risk percentage	34.00%	1.00%
Total Revenue [Member] \| Customer A [Member]
Concentration Risk [Line Items]
Concentration risk percentage		26.00%
Total Revenue [Member] \| Customer D [Member]
Concentration Risk [Line Items]
Concentration risk percentage	19.00%	18.00%
Total Revenue [Member] \| Customer L [Member]
Concentration Risk [Line Items]
Concentration risk percentage	16.00%	9.00%
Total Revenue [Member] \| Customer I [Member]
Concentration Risk [Line Items]
Concentration risk percentage	13.00%	2.00%
Total Revenue [Member] \| Customer M [Member]
Concentration Risk [Line Items]
Concentration risk percentage	11.00%	2.00%
Total Revenue [Member] \| Customer K [Member]
Concentration Risk [Line Items]
Concentration risk percentage		14.00%

Property and Equipment, Net - Summary of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 5,196	$ 5,180
Less accumulated depreciation and amortization	(4,801)	(4,881)
Property and equipment, net	395	299
Laboratory equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	2,348	2,404
Software and computer equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	477	424
Furniture and fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	85	147
Vehicles [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	204	203
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 2,082	$ 2,002

Investments and Fair Value Measurements - Summary of Amortized Cost and Fair Value of the Available-For-Sale Investment Securities Portfolio (Details) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	$ 21,072	$ 12,842
Unrealized Gains		0
Unrealized Losses		(1)
Estimated Fair Value	21,072	12,841
Cash Equivalents [Member] \| Money Market Funds [Member]
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	9,902	8,943
Unrealized Gains		0
Unrealized Losses		0
Estimated Fair Value	9,902	8,943
Cash Equivalents [Member] \| Commercial Paper [Member]
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	1,345
Estimated Fair Value	1,345
Short-term Investments [Member] \| Commercial Paper [Member]
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	6,776	1,399
Unrealized Gains		0
Unrealized Losses		0
Estimated Fair Value	6,776	1,399
Short-term Investments [Member] \| Treasury Bills [Member]
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	1,195	0
Unrealized Gains		0
Unrealized Losses		0
Estimated Fair Value	1,195	0
Short-term Investments [Member] \| Corporate Securities [Member]
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	656	0
Unrealized Gains		0
Unrealized Losses		0
Estimated Fair Value	656	0
Short-term Investments [Member] \| U.S. Government Securities [Member]
Schedule Of Available For Sale Securities [Line Items]
Amortized Cost	1,198	2,500
Unrealized Gains		0
Unrealized Losses		(1)
Estimated Fair Value	$ 1,198	$ 2,499

Investments and Fair Value Measurements - Additional Information (Detail)	Dec. 31, 2018 USD ($)
Investments Debt And Equity Securities [Abstract]
Investment in continuous unrealized loss position for more than twelve months	$ 0
Other-than-temporary impairments associated with credit losses required to be recognized	$ 0

Investments and Fair Value Measurements - Summary of Fair Value of Available-for-Sale Investments (Details) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Assets at Fair Value
Total Assets at Fair Value	$ 21,072	$ 12,841
Money Market Funds [Member]
Assets at Fair Value
Cash equivalents	9,902	8,943
Commercial Paper [Member]
Assets at Fair Value
Cash equivalents	1,345
Short-term investments	6,776	1,399
Treasury Bills [Member]
Assets at Fair Value
Short-term investments	1,195
U.S. Government Securities [Member]
Assets at Fair Value
Short-term investments	1,198	2,499
Level 1 [Member]
Assets at Fair Value
Total Assets at Fair Value	12,295	11,442
Level 1 [Member] \| Money Market Funds [Member]
Assets at Fair Value
Cash equivalents	9,902	8,943
Level 1 [Member] \| Commercial Paper [Member]
Assets at Fair Value
Cash equivalents	0
Short-term investments	0	0
Level 1 [Member] \| Treasury Bills [Member]
Assets at Fair Value
Short-term investments	1,195
Level 1 [Member] \| U.S. Government Securities [Member]
Assets at Fair Value
Short-term investments	1,198	2,499
Level 2 [Member]
Assets at Fair Value
Total Assets at Fair Value	8,777	1,399
Level 2 [Member] \| Money Market Funds [Member]
Assets at Fair Value
Cash equivalents	0	0
Level 2 [Member] \| Commercial Paper [Member]
Assets at Fair Value
Cash equivalents	1,345
Short-term investments	6,776	1,399
Level 2 [Member] \| Treasury Bills [Member]
Assets at Fair Value
Short-term investments	0
Level 2 [Member] \| U.S. Government Securities [Member]
Assets at Fair Value
Short-term investments	0	0
Level 3 [Member]
Assets at Fair Value
Total Assets at Fair Value	0	0
Level 3 [Member] \| Money Market Funds [Member]
Assets at Fair Value
Cash equivalents	0	0
Level 3 [Member] \| Commercial Paper [Member]
Assets at Fair Value
Cash equivalents	0
Short-term investments	0	0
Level 3 [Member] \| Treasury Bills [Member]
Assets at Fair Value
Short-term investments	0
Level 3 [Member] \| U.S. Government Securities [Member]
Assets at Fair Value
Short-term investments	0	$ 0
Corporate Securities [Member]
Assets at Fair Value
Short-term investments	656
Corporate Securities [Member] \| Level 1 [Member]
Assets at Fair Value
Short-term investments	0
Corporate Securities [Member] \| Level 2 [Member]
Assets at Fair Value
Short-term investments	656
Corporate Securities [Member] \| Level 3 [Member]
Assets at Fair Value
Short-term investments	$ 0

Investments and Fair Value of Financial Instruments - Summary of Changes in Fair Value and Other Adjustments of Liabilities (Detail) - Level 3 [Member] $ in Thousands	12 Months Ended
	Dec. 31, 2018 USD ($)
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Balance as of December 31, 2017	$ 0
Common stock and warrants issued in conjunction with securities purchase agreements	23,022
Change in fair value and other adjustments	(9,561)
Reclassification of common stock adjustment feature liability balance to equity	(8,378)
Balance as of December 31, 2018	5,083
Common Stock Warrant Liability [Member] \| Private Placement [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Balance as of December 31, 2017	0
Common stock and warrants issued in conjunction with securities purchase agreements	10,200
Change in fair value and other adjustments	(7,846)
Reclassification of common stock adjustment feature liability balance to equity	0
Balance as of December 31, 2018	2,354
Common Stock Warrant Liability [Member] \| June Offering [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Balance as of December 31, 2017	0
Common stock and warrants issued in conjunction with securities purchase agreements	9,022
Change in fair value and other adjustments	(6,293)
Reclassification of common stock adjustment feature liability balance to equity	0
Balance as of December 31, 2018	2,729
Common Stock Adjustment Feature Liability [Member] \| Private Placement [Member]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Balance as of December 31, 2017	0
Common stock and warrants issued in conjunction with securities purchase agreements	3,800
Change in fair value and other adjustments	4,578
Reclassification of common stock adjustment feature liability balance to equity	(8,378)
Balance as of December 31, 2018	$ 0

Adoption of ASC Topic 606, "Revenue from Contracts with Customers" - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Revenue Initial Application Period Cumulative Effect Transition [Line Items]
Impact to revenues	$ 1,464,000	$ 4,026,000
Topic 606 [Member]
Revenue Initial Application Period Cumulative Effect Transition [Line Items]
Impact of adoption of Topic 606 (Note 5)	$ 2,371,000
Topic 606 [Member] \| Revenue From License Agreement [Member] \| Minimum [Member]
Revenue Initial Application Period Cumulative Effect Transition [Line Items]
Revenue, remaining performance obligation, expected timing of satisfaction, period	10 years
Topic 606 [Member] \| Revenue From License Agreement [Member] \| Maximum [Member]
Revenue Initial Application Period Cumulative Effect Transition [Line Items]
Revenue, remaining performance obligation, expected timing of satisfaction, period	20 years
Topic 606 [Member] \| Difference between Revenue Guidance in Effect before and after Topic 606
Revenue Initial Application Period Cumulative Effect Transition [Line Items]
Impact to revenues	$ (328,000)

Variable Interest Entity - Additional Information (Detail)	1 Months Ended	12 Months Ended
	Feb. 29, 2012 Owner	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)
Variable Interest Entity [Line Items]
Variable interest entity agreement, terms		Both the Company and Bioceres incur expenses in support of specific activities agreed, as defined by joint work plans, which apply fair market value to each partner’s activities. Unequal contributions of services are equalized by the partners through cash payments. Verdeca is not the primary obligor for these activities performed by the Company or Bioceres. An agreement executed in conjunction with the formation of Verdeca specified that if Bioceres determines it requires cash to fund its contributed services (subject to certain annual limits), Bioceres, S.A. may elect to sell shares of its common stock to the Company for an amount not exceeding $5.0
Funding period of cash required for contributed services		4 years
Direct expenses and allocated overhead amount		$ 947,000	$ 912,000
Maximum [Member]
Variable Interest Entity [Line Items]
Commitment to purchase stock		$ 5,000,000
Bioceres, S.A. [Member]
Variable Interest Entity [Line Items]
Number of shareholders owning agricultural investment and development cooperative \| Owner	300

Accounts Payable and Accrued Expenses - Summary of Accounts Payable and Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Payables And Accruals [Abstract]
Accounts payable—trade	$ 285	$ 366
Payroll and benefits	1,096	805
Research and development	433	899
Royalty fees due to unrelated parties	187	177
Consulting	92	32
Rent and utilities	91	51
Legal	285	83
Accrued withholding taxes	0	24
Other	176	59
Total accounts payable and accrued expenses	$ 2,645	$ 2,496

Accounts Payable and Accrued Expenses - Exit or Disposal Activities - Additional Information (Details)	12 Months Ended
	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Dec. 31, 2016 USD ($) Position
Payables And Accruals [Line Items]
Number of positions eliminated \| Position			23
Other restructuring costs	$ 0	$ 0
One-Time Employee Termination Benefits [Member]
Payables And Accruals [Line Items]
Severance cost accrued under payroll and benefits			$ 389,000
One-Time Employee Termination Benefits [Member] \| Selling, General, and Administrative Expense [Member]
Payables And Accruals [Line Items]
Severance costs			192,000
Executive Employment Contract [Member] \| Selling, General, and Administrative Expense [Member]
Payables And Accruals [Line Items]
Severance costs			$ 224,000

Long-Term Debt - Term Loan - Additional Information (Detail) - USD ($)	1 Months Ended	12 Months Ended
	Jul. 31, 2017	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2015
Debt Instrument [Line Items]
Loss on extinguishment of debt			$ (900,000)
Repayment of accrued interest and prepayment fee			747,000
Accretion of debt discount			98,000
Senior Secured Term Loan Facility [Member]
Debt Instrument [Line Items]
Debt instrument, face amount				$ 25,000,000
Debt instrument end-of-term fee	$ 625,000
Debt instrument prepayment fee	$ 500,000
Loss on extinguishment of debt		$ (1,100,000)
Deferred loan issuance fees		41,000
Partially offset end of term fee previously amortized		267,000
Partially offset end of term fee previously amortized netting		$ 900,000
Repayment of accrued interest and prepayment fee			747,000
Accretion of debt discount			$ 98,000

Private Placement and Registered Direct Offering - Additional Information (Detail)							3 Months Ended	12 Months Ended
	Jun. 11, 2018 USD ($) $ / shares shares	May 11, 2018 USD ($) $ / shares shares	May 08, 2018 $ / shares shares	Apr. 23, 2018 $ / shares shares	Mar. 22, 2018 $ / shares shares	Mar. 19, 2018	Jun. 30, 2018 USD ($)	Dec. 31, 2018 USD ($) $ / shares shares	Feb. 15, 2019 shares	May 07, 2018 USD ($)	Dec. 31, 2013 $ / shares
Class Of Warrant Or Right [Line Items]
Warrants issued, exercise price \| $ / shares								$ 18.37			$ 330.40
Period of trading days taken for calculation of volume weighted average price								3 days
Percentage of volume weighted average price of common stock								80.00%
Percentage of volume weighted average price of warrant								110.00%
Proceeds from issuance of private placement								$ 10,000,000
Offering costs								$ 197,000
Stock price \| $ / shares								$ 32.52
Common stock no par value \| $ / shares
Initial loss recognized on liabilities								$ 4,000,000
Issuance of placement agent warrants								526,000
Proceeds from issuance initial public offering								50,000,000
Fair value of common stock warrants at inception								9,000,000
Offering cost, expense								2,555,000
Warrants [Member]
Class Of Warrant Or Right [Line Items]
Issuance of placement agent warrants								$ 526,000
Placement Agent [Member] \| Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant \| shares								15,038
Warrants issued, exercise price \| $ / shares								$ 41.5625
Offering costs								$ 1,800,000
Warrant, exercisable term								5 years
Placement Agent [Member] \| Warrants [Member] \| Subsequent Event [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant \| shares									15,038
June Placement Agent Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant \| shares								69,617
Warrants issued, exercise price \| $ / shares								$ 12.568
Offering costs								$ 1,600,000
Aggregate agent fee paid								$ 980,000
Warrant, exercisable term								5 years
Issuance of placement agent warrants								$ 427,000
Offering cost, expense								721,000
Offering costs portion attributable to common stock								$ 911,000
June Placement Agent Warrants [Member] \| Warrants [Member] \| Subsequent Event [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant \| shares									69,617
June Private Placement [Member] \| Warrants [Member] \| Subsequent Event [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant \| shares									1,392,345
Measurement Input, Price Volatility [Member]
Class Of Warrant Or Right [Line Items]
Volatility rate								1.00
Measurement Input, Risk Free Interest Rate [Member]
Class Of Warrant Or Right [Line Items]
Volatility rate								0.0263
Black Scholes Merton model [Member]
Class Of Warrant Or Right [Line Items]
Stock price \| $ / shares								$ 8.20
Black Scholes Merton model [Member] \| Measurement Input, Price Volatility [Member]
Class Of Warrant Or Right [Line Items]
Volatility rate								1.08
Black Scholes Merton model [Member] \| Measurement Input, Risk Free Interest Rate [Member]
Class Of Warrant Or Right [Line Items]
Volatility rate								0.0283
Common Stock Adjustment Feature Liability [Member] \| Monte Carlo Simulation Model [Member]
Class Of Warrant Or Right [Line Items]
Fair value of liabilities								$ 3,800,000
Common Stock Warrant Liability [Member]
Class Of Warrant Or Right [Line Items]
Liabilities marked to market value								2,700,000
Additional income (loss) on liabilities								6,300,000
Proceeds from issuance of common stock								5,000,000
Proceeds from issuance of common stock and warrants gross								14,000,000
Common Stock Warrant Liability [Member] \| Monte Carlo Simulation Model [Member]
Class Of Warrant Or Right [Line Items]
Fair value of liabilities								$ 10,200,000
Minimum [Member]
Class Of Warrant Or Right [Line Items]
Warrants issued, exercise price \| $ / shares								$ 8.322
Purchase price of common stock \| $ / shares								8.322
June Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Warrants issued, exercise price \| $ / shares								$ 10.7258
Offering costs								$ 1,200,000
Proceeds from issuance of common stock and warrants gross								14,000,000
Proceeds from issuance of common stock and warrants net								12,800,000
Private Placement [Member]
Class Of Warrant Or Right [Line Items]
Proceeds from issuance of private placement								8,700,000
Proceeds from offering costs of private placement, gross								10,000,000
Offering costs								1,300,000
Private Placement [Member] \| Warrants [Member]
Class Of Warrant Or Right [Line Items]
Offering costs								458,000
Private Placement [Member] \| Placement Agent [Member]
Class Of Warrant Or Right [Line Items]
Aggregate agent fee paid								850,000
Private Placement [Member] \| Common Stock Adjustment Feature Liability [Member]
Class Of Warrant Or Right [Line Items]
Liabilities marked to market value										$ 8,400,000
Additional income (loss) on liabilities							$ (2,400,000)
Reclassification of financing liabilities to stockholders equity							$ 8,400,000
Private Placement [Member] \| Common Stock Warrant Liability [Member]
Class Of Warrant Or Right [Line Items]
Liabilities marked to market value								2,400,000
Additional income (loss) on liabilities								7,900,000
Private Placement [Member] \| Securities Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued \| shares					300,752
Warrant issued, shares of common stock called by warrant \| shares					300,752
Warrants issued, exercise price \| $ / shares					$ 45.75
Warrants expiration period						5 years
Applicable VWAP CalculationsI in Accordance with Registration [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued \| shares				798,754
Warrant issued, shares of common stock called by warrant \| shares				799,300
Warrants issued, exercise price \| $ / shares				$ 17.2143
Applicable VWAP Calculations in Accordance Shareholder Approval [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued \| shares			1,201,634
Warrant issued, shares of common stock called by warrant \| shares			1,282,832
Warrants issued, exercise price \| $ / shares			$ 10.7258
June Offering [Member]
Class Of Warrant Or Right [Line Items]
Issuance of placement agent warrants								$ 427,000
June Offering [Member] \| June Purchase Agreement [Member]
Class Of Warrant Or Right [Line Items]
Shares of common stock issued \| shares	1,392,345
Stock price \| $ / shares	$ 9.93
Proceeds from issuance of common stock	$ 13,800,000
Offering closing period	Jun. 14, 2018
June Private Placement [Member] \| Warrants [Member]
Class Of Warrant Or Right [Line Items]
Warrant issued, shares of common stock called by warrant \| shares		1,392,345
Warrants issued, exercise price \| $ / shares		$ 9.94
Warrants expiration period		5 years 6 months
Proceeds from offering costs of private placement, gross		$ 174,000
Class of warrant or right number of securities called by warrants or rights, per share \| $ / shares		$ 0.125

Stock-Based Compensation and Warrants - Additional Information (Detail)				1 Months Ended	3 Months Ended	12 Months Ended
	May 20, 2015 shares	May 14, 2015	Jun. 30, 2014 $ / shares shares	Dec. 31, 2013 $ / shares shares	Sep. 30, 2018	Dec. 31, 2018 USD ($) IncentivePlan $ / shares shares	Dec. 31, 2017 USD ($) $ / shares shares	Dec. 31, 2016 shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of equity incentive plans \| IncentivePlan						2
Total number of options outstanding						530,044	288,129	228,939
Intrinsic value of options exercised \| $						$ 0	$ 0
Total grant-date fair value of shares vested \| $						1,300,000	$ 449,000
Unrecognized compensation cost related to unvested stock-based compensation grants \| $						$ 1,200,000
Weighted-average remaining recognition period						2 years 1 month 6 days
Weighted-average estimated grant-date fair value of stock options granted \| $ / shares						$ 6.65	$ 9.20
Stock-based compensation \| $						$ 1,550,000	$ 1,474,000
Number of warrant to purchase common stock issued						2,822,903
Warrants issued, exercise price \| $ / shares				$ 330.40		$ 18.37
June Purchase Agreement [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of warrant to purchase common stock issued						1,297,870
Warrants issued, exercise price \| $ / shares						$ 10.7258
Series D Redeemable Convertible Preferred Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Warrants issued, exercise price \| $ / shares			$ 363.20
Warrant issued, shares of common stock called by warrant			61,397
Warrant, exercisable term			5 years
Series D Redeemable Convertible Preferred Stock [Member] \| Placement Agent [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Warrants issued, exercise price \| $ / shares			$ 268.80
Warrant issued, shares of common stock called by warrant			1,674
Mahyco International [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Warrant issued, shares of common stock called by warrant				3,784
Warrant, expiration date				Dec. 11, 2018
2015 Employee Stock Purchase Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total number of shares reserved for issuance under plan							89,489
Stock-based compensation \| $						$ 11,000	$ 13,000
Percentage in payroll deductions to acquire shares of common stock		15.00%
Purchase plan offering period		6 months
Employees are able to purchase company's common stock on first trading day of offering period, percentage		85.00%
Issuance of common stock pursuant to employee stock purchase plan						6,853
First offering period, start date		May 14, 2015
First offering period, end date		Feb. 01, 2016
Private Placement [Member] \| June Purchase Agreement [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of warrant to purchase common stock issued						1,461,962
Private Placement [Member] \| June Purchase Agreement [Member] \| Purchase Price of $9.94 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of warrant to purchase common stock issued						1,392,345
Warrants issued, purchase price of warrants per share \| $ / shares						$ 9.94
Private Placement [Member] \| June Purchase Agreement [Member] \| Exercise Price of $12.568 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Number of warrant to purchase common stock issued						69,617
Warrants issued, exercise price \| $ / shares						$ 12.568
2015 Omnibus Equity Incentive Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Terms under the plan						The 2015 Plan became effective upon the Company’s IPO in May 2015 and all shares that were reserved, but not issued, under the 2006 Plan were assumed by the 2015 Plan. Upon effectiveness, the 2015 Plan had 154,387 shares of common stock reserved for future issuance, which included 10,637 that were transferred to and assumed by the 2015 Plan. The 2015 Plan provides for automatic annual increases in shares available for grant. In addition, shares subject to awards under the 2006 Plan that are forfeited or canceled will be added to the 2015 Plan.
Total number of shares reserved for issuance under plan	154,387					494,191
Options vesting period	4 years				2 years
Common stock available for future grant						26,349
Total number of options outstanding						467,842
2015 Omnibus Equity Incentive Plan [Member] \| Share-based Compensation Award, Tranche One [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock options vesting percentage at end of one year	25.00%
2006 Stock Incentive Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total number of shares reserved for issuance under plan	10,637
Total number of options outstanding						62,202
Maximum [Member] \| 2015 Omnibus Equity Incentive Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options exercisable period	10 years
Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Warrants issued, exercise price \| $ / shares						$ 8.322

Stock-Based Compensation and Warrants - Summary of Activity Under Stock Incentive Plans (Detail) - $ / shares	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Shares Subject to Outstanding, Beginning Balance	288,129	228,939
Shares Subject to Outstanding, Options granted	302,077	111,336
Shares Subject to Outstanding, Options exercised	(44,354)
Shares Subject to Outstanding, Options Forfeited	(4,006)	(24,334)
Shares Subject to Outstanding, Options Expired	(11,802)	(27,812)
Shares Subject to Outstanding, Ending Balance	530,044	288,129
Shares Subject to Outstanding, Vested and expected to vest	519,655
Shares Subject to Outstanding, Exercisable	183,300
Weighted-Average Exercise Price Per Share, Outstanding Beginning Balance	$ 63.62	$ 87.60
Weighted-Average Exercise Price Per Share, Options granted	6.65	9.20
Weighted-Average Exercise Price Per Share, Options exercised	21.73
Weighted-Average Exercise Price Per Share, Options forfeited	14.21	31.75
Weighted-Average Exercise Price Per Share, Options expired	43.73	98.95
Weighted Average Exercise Price Per Share, Outstanding Ending Balance	35.53	$ 63.62
Weighted Average Exercise Price Per Share, Vested and expected to vest	35.91
Weighted Average Exercise Price Per Share, Exercisable	$ 71.47

Stock-Based Compensation and Warrants - Weighted-Average Fair Value Assumption of Stock Option Awards (Detail) - Employee Stock Option [Member]	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected term (years)	5 years 11 months 26 days	6 years 1 month 13 days
Expected volatility	99.00%	79.00%
Risk-free interest rate	2.95%	1.90%

Commitments and Contingencies - Additional Information (Detail)		12 Months Ended
	Dec. 31, 2010 USD ($) Program	Dec. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Jun. 15, 2005 USD ($)
Commitments And Contingencies [Line Items]
Operating leases rent expense		$ 1,300,000	$ 1,200,000
Other noncurrent liability		3,072,000	3,000,000
Royalties due to both related and unrelated parties on license revenue accrued		216,000	206,000
Milestones payments yet to be achieved		2,000,000	2,000,000
Milestones payment		$ 0	$ 0
Anawah, Inc [Member]
Commitments And Contingencies [Line Items]
Contingent liability	$ 3,000,000			$ 5,000,000
Date of merger and reorganization		Jun. 15, 2005
Restructuring activities, description		As of December 31, 2010, the Company ceased activities relating to three of the six Anawah product programs
Number of development programs ceased \| Program	3
Number of development programs \| Program	6
Other noncurrent liability		$ 3,000,000
Minimum [Member]
Commitments And Contingencies [Line Items]
Operating leases, term of contract		1 year
Royalty payments due, percentage of net revenue as defined in the In-Licensing agreements		2.00%
Maximum [Member]
Commitments And Contingencies [Line Items]
Operating leases, term of contract		5 years
Royalty payments due, percentage of net revenue as defined in the In-Licensing agreements		15.00%

Commitments and Contingencies - Future Minimum Payments Under Non-Cancelable Operating Leases (Detail) $ in Thousands	Dec. 31, 2018 USD ($)
Operating Leases Future Minimum Payments Due [Abstract]
2019	$ 704
2020	713
2021	595
2022	497
2023	295
Total future minimum payments under non- cancelable operating leases	$ 2,804

Leases - Additional Information (Detail) - ASU No. 2016-02 [Member] - Subsequent Event [Member] $ in Millions	Jan. 01, 2019 USD ($)
Subsequent Event [Line Items]
Operating lease liability	$ 2.4
ROU asset	$ 2.3

Income Taxes - Components of Loss Before Income Taxes (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Income Tax Disclosure [Abstract]
Domestic	$ (13,470)	$ (15,681)
Foreign	0	0
Loss before income taxes	$ (13,470)	$ (15,681)

Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Schedule Of Income Tax [Line Items]
Total income tax expense	$ 10,000	$ 26,000
Decrease in net valuation allowance	$ (3,200,000)	$ 14,300,000
Corporate tax rate	21.00%	34.00%
Operating loss carryforwards limitations on use	it has not forfeited the right to carryforward tax losses up to 20 years
Tax years subject to examination to extent of NOLs being carried forward	2000
Uncertain Tax Position	$ 0
Federal [Member]
Schedule Of Income Tax [Line Items]
Aggregate amount of net operating loss	168,600,000
Operating loss carryforward generated	168,600,000
Operating loss carryforward unutilized	7,200,000
State [Member]
Schedule Of Income Tax [Line Items]
Aggregate amount of net operating loss	$ 123,200,000
Maximum [Member]
Schedule Of Income Tax [Line Items]
Corporate tax rate		35.00%
Right to carryforward tax losses, period	20 years
Tax year subject to examination by the tax authorities	2018
Minimum [Member]
Schedule Of Income Tax [Line Items]
Tax year subject to examination by the tax authorities	2000

Income Taxes - Schedule of Income Tax Expense Comprised of Current State Taxes and Foreign Taxes (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Current:
Federal	$ 0	$ 0
State	1,000	2,000
Foreign	9,000	24,000
Total current tax expense	10,000	26,000
Deferred:
Federal	0	0
State	0	0
Foreign	0	0
Total deferred tax benefit	0	0
Total tax expense	$ 10,000	$ 26,000

Income Taxes - Reconciliation of Statutory Federal Income Tax Rate to the Company's Effective Tax Rate (Detail)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Income Tax Disclosure [Abstract]
Expected income tax provision at the federal statutory rate	21.00%	34.00%
State taxes, net of federal benefit	8.50%	2.60%
Change in valuation allowance	(27.30%)	91.40%
Transaction costs	(2.90%)	0.00%
Related offering costs	(1.10%)	0.00%
Excess windfall benefit	1.40%	0.00%
Nondeductible expenses	0.00%	0.10%
Impact of change in federal tax rate	0.00%	(124.60%)
Withholding taxes	(0.10%)	(0.20%)
Other	0.40%	(3.50%)
Income tax provision	(0.10%)	(0.20%)

Income Taxes - Summary of Company's Deferred Tax Assets (Detail) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Deferred tax assets:
Net operating loss carryforwards	$ 42,097	$ 37,498
Unearned revenue	26	783
Stock-based compensation	2,855	2,273
Accrued payroll and benefits	255	51
Research and development credits	171	171
Fixed asset basis difference	114	128
Inventory reserve	508	396
Charitable contributions	3	3
Total deferred tax assets	46,029	41,303
Deferred tax liabilities:
Common stock warrant liabilities	(1,529)	0
Total deferred tax liabilities	(1,529)	0
Less valuation allowance	(44,500)	(41,303)
Net deferred tax assets	$ 0	$ 0

Retirement Benefits - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Compensation And Retirement Disclosure [Abstract]
Employer matching contribution, percent	50.00%
Maximum annual contribution per employee, percent	3.00%
Description of defined contribution pension and other postretirement plans	Employees’ rights to employer contributions vest on the one-year anniversary of their date of employment.
Defined benefit plan employee vested minimum period, years	1 year
Amount accrued for company's approved discretionary match	$ 0	$ 0

Segment and Geographic Information - Summary of Revenues Based on Location of Customers (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues	$ 1,464	$ 4,026
United States
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues	1,168	1,588
India
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues	90	1,064
Africa
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues	115	315
France
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues		220
Canada
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues	$ 91	181
China
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues		586
Belgium
Revenues From External Customers And Long Lived Assets [Line Items]
Total revenues		$ 72

Net Loss per Share - Summary of Securities Not Included in Diluted Per Share Calculations (Detail) - shares	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities not included in the diluted per share calculations, amount	3,352,947	354,974
Option to purchase common stock [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities not included in the diluted per share calculations, amount	530,044	288,129
Warrants to purchase common stock [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive securities not included in the diluted per share calculations, amount	2,822,903	66,845

Related Party Transactions - Additional Information (Detail) - USD ($)	Dec. 31, 2018	Dec. 31, 2017
Related Party Transaction [Line Items]
Royalty fees due	$ 29,000	$ 29,000
John Sperling Foundation [Member]
Related Party Transaction [Line Items]
Royalty fees due	$ 29,000
John Sperling Revocable Trust [Member]
Related Party Transaction [Line Items]
Royalty fees due		$ 29,000

Collaborative Arrangements - Additional Information (Detail)	1 Months Ended
	Aug. 31, 2017
Collaborative Arrangements [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contractual agreement month and year	2017-08

Summary of Significant Accounting Policies - Summary of Inventories (Detail) - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Inventory Disclosure [Abstract]
Raw Materials	$ 41	$ 45
Finished Goods	886	1,352
Inventories	$ 927	$ 1,397